Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | RGS4 | P49798 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22153693 | 0.76 | RGS4 (0.39) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL20216186 | 0.73 | ALDH1A1 (0.48) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL4011867 | 0.73 | ALDH1A1 (0.48) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL15473339 | 0.73 | RGS4 (0.33) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL3470129 | 0.71 | RGS4 (0.53) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL988699 | 0.71 | ALDH1A1 (0.46) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL1010796 | 0.71 | ALDH1A1 (0.46) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL14136363 | 0.71 | ALDH1A1 (0.46) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL9732689 | 0.70 | ALDH1A1 (0.44) | MGLLALDH1A1GMNNLMNAMAPT | |
| SCHEMBL3471705 | 0.68 | ALDH1A1 (0.43) | MGLLALDH1A1GMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198671-A1 | PROTECTED ANTIBODY-DRUG AND APTAMER-DRUG CONJUGATES | KOSAK KENNETH MICHAEL (US) | 2021-07-01 | — | — | US | disclosed |
| WO-2008103409-A2 | COMPOSITIONS OF CHLOROQUINE COUPLED TO ANTIBODIES AND TO OTHER PROTEINS WITH METHODS FOR THEIR SYNTHESIS | KOSAK KEN M | 2008-08-28 | — | — | WO | disclosed |
| US-20080051323-A1 | Chloroquine drug compositions and methods for their synthesis | KOSAK KENNETH M | 2008-02-28 | — | — | US | disclosed |
| US-20070166281-A1 | Chloroquine coupled antibodies and other proteins with methods for their synthesis | KOSAK KENNETH M | 2007-07-19 | — | — | US | disclosed |
| US-20070060499-A1 | Chloroquine combination drugs and methods for their synthesis | KOSAK KENNETH M | 2007-03-15 | — | — | US | disclosed |
| US-20060040879-A1 | Chloroquine coupled nucleic acids and methods for their synthesis | KOSAK KENNETH M | 2006-02-23 | — | — | US | disclosed |
| US-20050153913-A1 | Nucleic acid carrier compositions and methods for their synthesis | KOSAK KENNETH M (US) | 2005-07-14 | — | — | US | disclosed |
| US-20010034333-A1 | Cyclodextrin polymer compositions for use as drug carriers | KOSAK KENNETH M (US) | 2001-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034333-A1 | Cyclodextrin polymer compositions for use as drug carriers | ABCB1, ABCG2, CTTN | MGLL 3245/4885ALDH1A1 2419/4885GMNN 1858/4885 |
| US-20070166281-A1 | Chloroquine coupled antibodies and other proteins with methods for their synthesis | GPR119, CLTA, CHMP4B | MGLL 2059/4885ALDH1A1 4840/4885GMNN 3629/4885 |
| US-20070060499-A1 | Chloroquine combination drugs and methods for their synthesis | CHMP4B, CTSA, CLTA | MGLL 1359/4885ALDH1A1 4767/4885GMNN 3632/4885 |
| US-20080051323-A1 | Chloroquine drug compositions and methods for their synthesis | CHMP4B, CTSA, CLTA | MGLL 1181/4885ALDH1A1 4743/4885GMNN 3397/4885 |
| US-20210198671-A1 | PROTECTED ANTIBODY-DRUG AND APTAMER-DRUG CONJUGATES | ZFR, APP, RBM26 | MGLL 4639/4885ALDH1A1 1853/4885GMNN 2456/4885 |
| US-20060040879-A1 | Chloroquine coupled nucleic acids and methods for their synthesis | TLR9, TLR3, EXOSC5 | MGLL 2719/4885ALDH1A1 4696/4885GMNN 2069/4885 |
| US-20050153913-A1 | Nucleic acid carrier compositions and methods for their synthesis | DNA2, POLRMT, SLC29A2 | MGLL 2703/4885ALDH1A1 2130/4885GMNN 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.