Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 6/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009491 | 0.86 | MAPK1 (0.66) | MAPK1L3MBTL1ALDH1A1POLBTHRB | |
| SCHEMBL16519819 | 0.86 | MAPK1 (0.74) | MAPK1L3MBTL1ALDH1A1POLBTHRB | |
| SCHEMBL16592108 | 0.86 | MAPK1 (0.66) | MAPK1L3MBTL1ALDH1A1POLBTHRB | |
| SCHEMBL9108593 | 0.83 | MAPT (0.57) | MAPK1THRBKMT2AHPGDLIPE | |
| SCHEMBL31143143 | 0.83 | MAPT (0.57) | MAPK1THRBKMT2AHPGDLIPE | |
| SCHEMBL1011635 | 0.83 | MAPK1 (0.50) | MAPK1L3MBTL1ALDH1A1POLBTHRB | |
| SCHEMBL27233695 | 0.82 | MAPK1 (0.43) | MAPK1L3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL14810263 | 0.82 | MAPK1 (0.53) | MAPK1L3MBTL1THRBKMT2ATSHR | |
| SCHEMBL1010964 | 0.82 | THRB (0.57) | MAPK1L3MBTL1ALDH1A1POLBTHRB | |
| SCHEMBL27040222 | 0.81 | MAPK1 (0.59) | MAPK1L3MBTL1ALDH1A1POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554674-A1 | BIARYL ETHER UREA COMPOUNDS AS FAAH INHIBITORS | Jazz Pharmaceuticals Ireland Limited (IE) | 2025-05-21 | — | — | EP | disclosed |
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | NEUROPN THERAPEUTICS (US) | 2024-06-04 | — | — | US | disclosed |
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | NEUROPN THERAPEUTICS (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | Jazz Pharmaceuticals Therapeutics, Inc. | 2024-01-25 | — | — | US | disclosed |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | Jazz Pharmaceuticals Therapeutics, Inc. | 2024-01-25 | — | — | US | disclosed |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | Jazz Pharmaceuticals Therapeutics, Inc. | 2024-01-25 | — | — | US | disclosed |
| WO-2024013567-A1 | BIARYL ETHER UREA COMPOUNDS AS FAAH INHIBITORS | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-01-18 | — | — | WO | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-20150065464-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2015-03-05 | — | — | US | disclosed |
| WO-2013042139-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013042139-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-03-28 | — | — | WO | disclosed |
| US-8044052-B2 | Inhibitors of fatty acid amide hydrolase; N-pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzylidene)piperidine-1-carboxamide; elevate brain anandamide levels; pain, urinary incontinence, cognitive disorders, anxiety, depression, sleeping, eating, movement disorders, glaucoma, psoriasis | PFIZER INC. (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2276736-A1 | 4- [3- (ARYLOXY) BENZYLIDEN]-3-METHYL PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | Pfizer Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2276737-A1 | 4- [3- (ARYLOXY) BENZYLIDENE]-3-METHYL PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | Pfizer Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2076508-B1 | BIARYL ETHER UREA COMPOUNDS | PFIZER PROD INC (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009127949-A1 | 4- [3- (ARYLOXY) BENZYLIDENE] -3-METHYL PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| EP-2076508-A2 | BIARYL ETHER UREA COMPOUNDS | Pfizer Products Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| US-20080261941-A1 | Biaryl Ether Urea Compounds | Jazz Pharmaceuticals Therapeutics, Inc. | 2008-10-23 | — | — | US | disclosed |
| WO-2008047229-A2 | BIARYL ETHER UREA COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | FAAH, FAAH2, FAH | MAPK1 4121/4885L3MBTL1 4064/4885ALDH1A1 309/4885 |
| US-20150065464-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | FAAH, FAAH2, TPH1 | MAPK1 1136/4885L3MBTL1 1638/4885ALDH1A1 2023/4885 |
| US-20080261941-A1 | Biaryl Ether Urea Compounds | FAAH, FAAH2, LIPC | MAPK1 3199/4885L3MBTL1 4652/4885ALDH1A1 360/4885 |
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, HPGDS | MAPK1 3609/4885L3MBTL1 4672/4885ALDH1A1 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.