SCHEMBL10114680

SCHEMBL10114680

Cc1ccc2[nH]c3ccc(C(C)c4ccsc4)cc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.41
ACHE P22303 2/20 0.41
MLKL Q8NB16 1/20 0.39
MEN1 O00255 2/20 0.38
NPC1 O15118 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
ALDH1A1 P00352 6/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 4/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALOX15 P16050 1/20 0.36
GAA P10253 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10114707 0.79 MLKL (0.52) KIF11ACHEMLKLMEN1NPC1
SCHEMBL10114705 0.77 ACHE (0.58) KIF11ACHEMLKLMEN1NPC1
SCHEMBL22756732 0.76 KIF11 (0.53) KIF11ACHEMLKLMEN1NPC1
SCHEMBL10114713 0.75 KDM4E (0.53) KIF11ACHEMEN1NPC1KMT2A
SCHEMBL10114722 0.75 BCHE (0.50) KIF11ACHEMLKLMEN1NPC1
SCHEMBL10114678 0.74 KIF11 (0.45) KIF11ACHEMLKLMEN1NPC1
SCHEMBL16945407 0.74 TRPA1 (0.36) MEN1NPC1KMT2APOLBALDH1A1
SCHEMBL16451442 0.72 EIF4A3 (0.36) MEN1NPC1KMT2AALDH1A1MAPT
SCHEMBL345690 0.72 KIF11 (0.67) KIF11ACHEMEN1NPC1KMT2A
SCHEMBL29362354 0.72 KIF11 (0.67) KIF11ACHEMEN1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722841-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-13 US disclosed
US-8674052-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20130122710-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-16 US disclosed
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed