SCHEMBL10114713

SCHEMBL10114713

COc1ccc(C(C)c2ccc3[nH]c4ccc(C)cc4c3c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 5/20 0.53
MEN1 O00255 4/20 0.53
MAPT P10636 4/20 0.53
KMT2A Q03164 4/20 0.53
HSD17B10 Q99714 2/20 0.53
TSHR P16473 1/20 0.53
GFER P55789 1/20 0.53
HPGD P15428 4/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
APOBEC3A P31941 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ACHE P22303 7/20 0.42
KIF11 P52732 1/20 0.42
GAA P10253 1/20 0.42
CHUK O15111 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10114707 0.83 MLKL (0.52) KDM4EALDH1A1MEN1MAPTKMT2A
Glycozoline SCHEMBL11981403 0.81 ALDH1A1 (0.81) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL10114705 0.81 ACHE (0.58) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL10114722 0.79 BCHE (0.50) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL10114678 0.78 KIF11 (0.45) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL22756732 0.77 KIF11 (0.53) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL2680573 0.77 ACHE (0.68) KDM4EALDH1A1MAPTKMT2ATSHR
7-Methoxy-3-Methylcarbazole SCHEMBL602038 0.76 KDM4E (0.67) KDM4EALDH1A1MEN1MAPTKMT2A
7-Methoxy-3-Methylcarbazole SCHEMBL31214611 0.76 KDM4E (0.67) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL10114680 0.75 KIF11 (0.41) KDM4EALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722841-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-13 US disclosed
US-8674052-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20130122710-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-16 US disclosed
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed