SCHEMBL1011782

SCHEMBL1011782

Nc1ccc(N=Nc2ccc(N(CCO)CCO)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.52
KMT2A Q03164 8/20 0.52
TDP1 Q9NUW8 8/20 0.52
RAB9A P51151 7/20 0.52
NPC1 O15118 7/20 0.52
MEN1 O00255 6/20 0.52
L3MBTL1 Q9Y468 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
PSMD14 O00487 2/20 0.46
MITF O75030 1/20 0.46
PKM P14618 1/20 0.45
HTT P42858 1/20 0.45
MAPK1 P28482 5/20 0.44
ALDH1A1 P00352 5/20 0.44
CYP3A4 P08684 3/20 0.44
TSHR P16473 2/20 0.44
RECQL P46063 1/20 0.44
GFER P55789 1/20 0.44
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4931488 1.00 MAPT (0.52) MAPTKMT2ATDP1RAB9ANPC1
SCHEMBL33874 0.88 ALDH1A1 (0.54) MAPTKMT2ATDP1RAB9ANPC1
SCHEMBL8521178 0.88 ALDH1A1 (0.54) MAPTKMT2ATDP1RAB9ANPC1
SCHEMBL28087334 0.88 ALDH1A1 (0.54) MAPTKMT2ATDP1RAB9ANPC1
SCHEMBL2043151 0.88 CA12 (0.49) MAPTKMT2ATDP1RAB9ANPC1
SCHEMBL33796 0.86 ALDH1A1 (0.52) MAPTKMT2ATDP1RAB9ANPC1
Hydrochloric Acid SCHEMBL8756114 0.86 ALDH1A1 (0.52) MAPTKMT2ATDP1RAB9ANPC1
Hydrochloric Acid SCHEMBL7714474 0.86 ALDH1A1 (0.52) MAPTKMT2ATDP1RAB9ANPC1
Water SCHEMBL3359653 0.86 ALDH1A1 (0.52) MAPTKMT2ATDP1RAB9ANPC1
SCHEMBL13297216 0.85 KMT2A (0.46) MAPTKMT2ATDP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116322619-B Hair dyeing composition with improved durability 花王株式会社 2026-05-12 CN claimed
CN-121575607-A Method for improving printing effect of pure polyester printing 绵阳佳禧印染有限责任公司 2026-02-27 CN claimed
EP-4452210-B1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KAO CORP (JP) 2026-01-14 EP claimed
EP-3723864-B1 THICKENED ONE-COMPONENT HAIR TONER HENKEL AG & CO KGAA (DE) 2026-01-14 EP claimed
US-20250354302-A1 Fadable Multifunctional Monofilament Having a Core-Shell Structure CELANESE XINGDA FILAMENTS CO LTD (CN) 2025-11-20 US claimed
EP-4650500-A1 FADABLE MULTIFUNCTIONAL MONOFILAMENT HAVING A CORE-SHELL STRUCTURE Celanese Xingda Filaments Co., Ltd (CN) 2025-11-19 EP claimed
EP-4408377-B1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORP (JP) 2025-10-08 EP claimed
US-12383478-B2 Cosmetic product for dyeing keratin fibers KAO CORPORATION (JP) 2025-08-12 US claimed
US-12383480-B2 Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof KAO CORPORATION (JP) 2025-08-12 US claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
EP-0739622-B1 Hair dye composition WELLA AG (DE) 2001-06-20 EP claimed
WO-2000038636-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
US-5965114-A DYE CONTAINING MASS OF COSMETIC CARRIER AND 5-BROMO-4-CHLORO-3-INDOLYL-B-D-GALACTOSIDE; READY-TO-USE DYE IS OBTAINED BY MIXING THE DYE CONTAINING MASS WITH A HYDROLASE ENZYME; EASILY CONVERTED INDIGO DYE PRECURSOR WELLA AG (DE) 1999-10-12 US claimed
EP-0843993-A2 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1998-05-27 EP claimed
EP-0843994-A2 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1998-05-27 EP claimed
US-5637115-A Oxidation hair dye compositions containing developers, couplers, and AZO dyes WELLA AKTIENGESELLSCHAT (DE) 1997-06-10 US claimed
EP-0739622-A1 Hair dye composition Wella Aktiengesellschaft (DE) 1996-10-30 EP claimed
EP-0480829-B1 Hair dyeing composition containing anthraquinones OREAL (FR) 1994-04-06 EP claimed
US-5226924-A 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM L'OREAL (FR) 1993-07-13 US claimed
EP-0480829-A1 Hair dyeing composition containing anthraquinones L'OREAL (FR) 1992-04-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12383478-B2 Cosmetic product for dyeing keratin fibers KRT18, H1-2, H1-0 MAPT 662/4885KMT2A 699/4885TDP1 1264/4885
US-12383480-B2 Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof KRT18, PRKCH, PRKCE MAPT 2075/4885KMT2A 124/4885TDP1 2593/4885
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 MAPT 654/4885KMT2A 3273/4885TDP1 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.