Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 4/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23142701 | 0.85 | RAB9A (0.39) | RAB9AHCRTR2POLBL3MBTL1TSHR | |
| SCHEMBL18458207 | 0.81 | RAB9A (0.41) | RAB9APOLBL3MBTL1ACE2ACE | |
| SCHEMBL22815872 | 0.81 | HCRTR2 (0.41) | RAB9AHCRTR2POLBL3MBTL1 | |
| SCHEMBL24922942 | 0.81 | HSD17B10 (0.44) | POLBL3MBTL1HSD17B10TSHRALDH1A1 | |
| SCHEMBL24922956 | 0.81 | HSD17B10 (0.44) | POLBL3MBTL1HSD17B10TSHRALDH1A1 | |
| SCHEMBL27325529 | 0.80 | RAB9A (0.39) | RAB9AHCRTR2POLBL3MBTL1ACE2 | |
| SCHEMBL23569770 | 0.79 | L3MBTL1 (0.39) | RAB9AHCRTR2POLBL3MBTL1ACE2 | |
| SCHEMBL23142700 | 0.78 | HCRTR2 (0.46) | RAB9AHCRTR2POLBL3MBTL1MAPT | |
| SCHEMBL23735649 | 0.77 | RAB9A (0.34) | RAB9AHCRTR2POLBL3MBTL1 | |
| SCHEMBL16790988 | 0.77 | JAK3 (0.41) | RAB9AHCRTR2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016937-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | TORAY INDUSTRIES, INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| US-20180036409-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | BONAC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| US-20170349902-A1 | SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR INHIBITING TGF-BETA1 EXPRESSION | BONAC CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20160319282-A1 | ARTIFICIAL MATCH-TYPE miRNA FOR CONTROLLING GENE EXPRESSION AND USE THEREFOR | BONAC CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160304866-A1 | Drug for Disease Caused by Expression of Periostin Except Eye Disease, and Use Thereof | AQUA THERAPEUTICS CO., LTD. (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160108400-A1 | Single-Stranded Nucleic Acid Molecule for Controlling Gene Expression | BONAC CORPORATION (JP) | 2016-04-21 | — | — | US | disclosed |
| US-9206422-B2 | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | BONAC CORPORATION (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9200278-B2 | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | BONAC CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20150105442-A1 | Nucleic Acid Molecule Capable of Inhibiting Expression of Periostin Gene, method for Inhibiting Expression of Periostin Gene, and Use of Said Nucleic Acid Molecule | AQUA THERAPEUTICS CO., LTD. (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20150011605-A1 | Single-Stranded Nucleic Acid Molecule for Controlling Gene Expression | BONAC CORPORATION (JP) | 2015-01-08 | — | — | US | disclosed |
| US-8785121-B2 | Single-stranded nucleic acid molecule for controlling gene expression | BONAC CORPORATION (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20140171486-A1 | Single-Stranded Nucleic Acid Molecule Having Nitrogen-Containing Alicyclic Skeleton | BONAC CORPORATION (JP) | 2014-06-19 | — | — | US | disclosed |
| US-20140171633-A1 | Single-Stranded Nucleic Acid Molecule Having Nitrogen-Containing Alicyclic Skeleton | BONAC CORPORATION (JP) | 2014-06-19 | — | — | US | disclosed |
| US-8691782-B2 | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | BONAC CORPORATION (JP) | 2014-04-08 | — | — | US | disclosed |
| US-20120035246-A1 | SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING NITROGEN-CONTAINING ALICYCLIC SKELETON | BONAC CORPORATION (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120010271-A1 | SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION | BONAC CORPORATION (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010271-A1 | SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION | SRRT, SSU72, RPRD2 | RAB9A 4274/4885HCRTR2 4029/4885POLB 505/4885 |
| US-20180036409-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | NSUN2, POLRMT, POLN | RAB9A 3499/4885HCRTR2 4665/4885POLB 6/4885 |
| US-20240016937-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | NSUN2, POLRMT, POLN | RAB9A 3499/4885HCRTR2 4665/4885POLB 6/4885 |
| US-20140171633-A1 | Single-Stranded Nucleic Acid Molecule Having Nitrogen-Containing Alicyclic Skeleton | NSUN2, CTDSP1, RNGTT | RAB9A 4285/4885HCRTR2 2261/4885POLB 112/4885 |
| US-20120035246-A1 | SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING NITROGEN-CONTAINING ALICYCLIC SKELETON | NSUN2, CTDSP1, RNGTT | RAB9A 4285/4885HCRTR2 2261/4885POLB 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.