Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 12/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118875 | 0.87 | CASP1 (0.61) | ADAM17CASP1CASP8CCR1 | |
| SCHEMBL10119268 | 0.86 | CTSB (0.46) | ADAM17CCR1CTSB | |
| SCHEMBL10118872 | 0.80 | CTSB (0.44) | CTSB | |
| SCHEMBL10118858 | 0.80 | MAOA (0.39) | CTSB | |
| SCHEMBL10119061 | 0.77 | CCR1 (0.42) | ADAM17CASP1CCR1CTSB | |
| SCHEMBL10118870 | 0.76 | ACACB (0.39) | CTSB | |
| SCHEMBL8638326 | 0.76 | CA2 (0.55) | ADAM17 | |
| SCHEMBL10118876 | 0.75 | ABL1 (0.41) | CTSB | |
| SCHEMBL10118844 | 0.75 | CTSL (0.55) | CASP1CTSB | |
| SCHEMBL10119021 | 0.73 | GPR132 (0.40) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |