Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 3/20 | 0.46 |
| ▸ | CPT1A | P50416 | 3/20 | 0.46 |
| ▸ | EP300 | Q09472 | 4/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.39 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844903 | 0.92 | EP300 (0.51) | CPT2CPT1AEP300CREBBPMAPT | |
| SCHEMBL873777 | 0.87 | EP300 (0.49) | CPT2CPT1AEP300CREBBPPABPC1 | |
| SCHEMBL10119687 | 0.83 | CYP2C9 (0.44) | EP300CREBBPHDAC8PABPC1ALDH1A1 | |
| SCHEMBL844882 | 0.81 | PABPC1 (0.59) | CPT2CPT1AEP300CREBBPPABPC1 | |
| SCHEMBL845110 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAPFKFB2PFKFB1PFKFB3 | |
| SCHEMBL871785 | 0.78 | HCRTR1 (0.43) | EP300CREBBPPABPC1CFDALDH1A1 | |
| SCHEMBL10119326 | 0.78 | EP300 (0.41) | EP300CREBBPCFDALDH1A1LMNA | |
| SCHEMBL872886 | 0.77 | KDM4E (0.52) | PABPC1ALDH1A1LMNAPFKFB2PFKFB1 | |
| SCHEMBL13272439 | 0.76 | HCRTR1 (0.38) | HDAC8ALDH1A1PFKFB2PFKFB1PFKFB3 | |
| SCHEMBL23373375 | 0.76 | PFKFB3 (0.55) | PFKFB2PFKFB1PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |