Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.43 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.43 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845295 | 0.90 | KDM4E (0.61) | KDM4ELMNAPABPC1ALDH1A1GAA | |
| SCHEMBL844873 | 0.88 | NPC1 (0.63) | LMNAPABPC1ALDH1A1NPC1MAPK1 | |
| SCHEMBL10119687 | 0.86 | CYP2C9 (0.44) | PABPC1ALDH1A1NPC1MAPK1HTT | |
| SCHEMBL872930 | 0.83 | GAA (0.52) | KDM4ELMNAPABPC1GAAMAPK1 | |
| SCHEMBL871771 | 0.81 | PABPC1 (0.44) | KDM4ELMNAPABPC1ALDH1A1GAA | |
| SCHEMBL873856 | 0.81 | HCRTR1 (0.45) | ALDH1A1MAPK1HTTTSHRMEN1 | |
| SCHEMBL845110 | 0.81 | ALDH1A1 (0.48) | KDM4ELMNAALDH1A1HSD17B10KDM1A | |
| SCHEMBL874313 | 0.80 | MAPK1 (0.50) | LMNAALDH1A1GAAMAPK1HTT | |
| SCHEMBL845313 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10119595 | 0.80 | SCN3A (0.43) | NPC1PFKFB3PFKFB2PFKFB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |