Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765543 | 0.92 | BDKRB1 (0.53) | BDKRB1MAPK14HDAC6CYP3A4RXRA | |
| SCHEMBL765624 | 0.86 | MAPK14 (0.53) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL765612 | 0.79 | BDKRB1 (0.45) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL765837 | 0.79 | BDKRB1 (0.46) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL764461 | 0.77 | BDKRB1 (0.61) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL764501 | 0.76 | BDKRB1 (0.49) | BDKRB1MAPK14CYP3A4 | |
| SCHEMBL12239067 | 0.76 | BDKRB1 (0.60) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL10121171 | 0.76 | BDKRB1 (0.46) | BDKRB1MAPK14CYP3A4 | |
| SCHEMBL10121140 | 0.76 | BDKRB1 (0.41) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL764474 | 0.76 | BDKRB1 (0.54) | BDKRB1MAPK14CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |