Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123568 | 0.72 | PDK1 (0.44) | LMNAGAAMAPTHTTKDM4E | |
| SCHEMBL10123576 | 0.69 | GAA (0.34) | LMNAGAAMAPTHTTKDM4E | |
| SCHEMBL10123569 | 0.68 | ALDH1A1 (0.45) | LMNAGAAMAPTHTTKDM4E | |
| SCHEMBL10122196 | 0.68 | ACLY (0.41) | MTNR1ALMNAGAAMAPTHTT | |
| SCHEMBL10123534 | 0.66 | GAA (0.43) | GAAMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL8306057 | 0.66 | MTNR1A (0.45) | ABCB1FLT1MTNR1ALMNAHTT | |
| SCHEMBL7431136 | 0.65 | MRGPRX1 (0.48) | ABCB1FLT1MTNR1ALMNAMAPT | |
| SCHEMBL10123461 | 0.65 | MEN1 (0.38) | LMNAGAAMAPTHTTKDM4E | |
| Hydrochloric Acid SCHEMBL2461132 | 0.64 | MTNR1A (0.44) | MTNR1ALMNAHTTMRGPRX1KDM4E | |
| SCHEMBL10123578 | 0.64 | GAA (0.42) | LMNAGAAMAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060820-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2012-05-10 | — | — | WO | disclosed |