SCHEMBL10130378

SCHEMBL10130378

CCc1cc2ccccc2c2c1oc1ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 6/20 0.43
GLA P06280 1/20 0.43
MAPT P10636 5/20 0.40
TSHR P16473 4/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
HPGD P15428 2/20 0.39
MAOA P21397 2/20 0.39
KDM4E B2RXH2 4/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
USP2 O75604 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
GAA P10253 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17589500 0.88 KMT2A (0.36) L3MBTL1ALDH1A1GLAMAPTTSHR
SCHEMBL30645481 0.88 GPR84 (0.45) L3MBTL1TDP1ALDH1A1GLAMAPT
SCHEMBL10130376 0.88 GPR84 (0.45) L3MBTL1TDP1ALDH1A1GLAMAPT
SCHEMBL23776250 0.87 ALDH1A1 (0.43) L3MBTL1TDP1ALDH1A1GLAMAPT
SCHEMBL18717945 0.86 KMT2A (0.45) L3MBTL1TDP1ALDH1A1MAPTTSHR
SCHEMBL24751343 0.81 GPR55 (0.50) L3MBTL1TDP1MAPT
SCHEMBL16283913 0.78 TDP1 (0.45) L3MBTL1TDP1ALDH1A1LMNAHTT
SCHEMBL18086413 0.76 L3MBTL1 (0.46) L3MBTL1TDP1ALDH1A1GLAMAPT
SCHEMBL26243611 0.76 TSHR (0.44) L3MBTL1ALDH1A1GLAMAPTTSHR
SCHEMBL26243614 0.76 CYP1A2 (0.41) L3MBTL1TDP1ALDH1A1GLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180076394-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-15 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180076394-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SUN2, LEF1, TRPA1 L3MBTL1 978/4885TDP1 2702/4885ALDH1A1 456/4885
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 L3MBTL1 2056/4885TDP1 2470/4885ALDH1A1 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.