Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144562 | 0.88 | LMNA (0.34) | SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL3344201 | 0.79 | — | — | |
| SCHEMBL14074860 | 0.69 | — | — | |
| SCHEMBL12509456 | 0.69 | EPHX2 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL17812991 | 0.69 | POLB (0.41) | ALDH1A1GAA | |
| SCHEMBL17812990 | 0.68 | DPP4 (0.32) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13283576 | 0.68 | CPB2 (0.31) | — | |
| SCHEMBL27429752 | 0.67 | FAP (0.34) | KDM4EALDH1A1 | |
| SCHEMBL15765258 | 0.67 | — | — | |
| SCHEMBL28623928 | 0.66 | POLB (0.32) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404896-A1 | CYCLOHEXANE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM | Shionogi&Co., Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |