Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | SELL | P14151 | 2/20 | 0.33 |
| ▸ | SELP | P16109 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144560 | 0.88 | SMN1; SMN2 (0.37) | LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3344201 | 0.81 | — | — | |
| SCHEMBL28623928 | 0.71 | POLB (0.32) | LMNAALDH1A1 | |
| SCHEMBL12041279 | 0.70 | L3MBTL1 (0.34) | LMNAPLGPLATALDH1A1SMN1; SMN2 | |
| SCHEMBL17812990 | 0.70 | DPP4 (0.32) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27429752 | 0.69 | FAP (0.34) | ALDH1A1 | |
| SCHEMBL1107370 | 0.67 | — | — | |
| SCHEMBL14074860 | 0.67 | — | — | |
| SCHEMBL13448573 | 0.67 | ADH1B (0.30) | — | |
| SCHEMBL10903234 | 0.66 | KDM4E (0.42) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653125-B2 | Cyclohexane derivative having NPY Y5 receptor antagonism | SHIONOGI CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2404896-A1 | CYCLOHEXANE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM | Shionogi&Co., Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |