Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677466 | 0.80 | MAPK1 (0.75) | MAPK1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL6693561 | 0.76 | AURKA (0.82) | MAPK1ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL15070209 | 0.75 | MAPK1 (0.67) | MAPK1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL6689634 | 0.75 | MAPK1 (0.63) | MAPK1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL15070211 | 0.74 | ALDH1A1 (0.71) | MAPK1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL14133024 | 0.74 | NPSR1 (0.76) | MAPK1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6679218 | 0.73 | MAPK1 (0.64) | MAPK1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL6683128 | 0.72 | L3MBTL1 (0.73) | NPC1RAB9AALDH1A1MAPTUSP2 | |
| SCHEMBL12264890 | 0.72 | MAPT (1.00) | MAPK1PPARGALDH1A1MAPTNPSR1 | |
| SCHEMBL22331103 | 0.72 | NPSR1 (0.86) | MAPK1NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPK1 3681/4885NPC1 764/4885RAB9A 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.