Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.44 |
| ▸ | APEH | P13798 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830073 | 0.82 | HTR6 (0.46) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL1599348 | 0.76 | HTR6 (0.50) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL26054592 | 0.73 | PPME1 (0.46) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL10176180 | 0.73 | HTR6 (0.47) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL14375312 | 0.72 | HTR6 (0.47) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL14760380 | 0.72 | HTR6 (0.50) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL28139909 | 0.72 | PPME1 (0.51) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL1599343 | 0.72 | HTR6 (0.50) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL28189646 | 0.72 | HTR6 (0.50) | PPME1HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL10466733 | 0.71 | RAPGEF4 (0.76) | PPME1HTR6MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115869-A1 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115869-A1 | TETRAZOLE DERIVATIVES | TSLP, IL5, CMA1 | PPME1 3977/4885HTR6 2365/4885MEN1 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.