Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100652 | 0.91 | HCAR2 (0.44) | HCAR2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL102082 | 0.91 | RAB9A (0.44) | HCAR2AKR1C3AKR1C2RAB9ALTB4R | |
| SCHEMBL102147 | 0.90 | LTB4R (0.44) | HCAR2MEN1KMT2AMAPTLTB4R | |
| SCHEMBL98766 | 0.89 | LTB4R (0.52) | HCAR2MEN1KMT2AMAPTLTB4R | |
| SCHEMBL99813 | 0.89 | HCAR2 (0.44) | HCAR2HTTRAB9AMAPT | |
| SCHEMBL99078 | 0.87 | HCAR2 (0.42) | HCAR2MEN1KMT2ALMNAHTT | |
| SCHEMBL99712 | 0.86 | HDAC1 (0.40) | HCAR2MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL100027 | 0.86 | GAA (0.39) | HCAR2MEN1KMT2AGAALMNA | |
| SCHEMBL102617 | 0.86 | HCAR2 (0.39) | HCAR2MEN1KMT2ARAB9APOLB | |
| SCHEMBL99669 | 0.86 | NPC1 (0.45) | HCAR2MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |