Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99813 | 0.90 | HCAR2 (0.44) | HDAC1HCAR2HTT | |
| SCHEMBL101458 | 0.86 | HCAR2 (0.45) | KMT2AALDH1A1L3MBTL1HCAR2LMNA | |
| SCHEMBL99713 | 0.85 | MLYCD (0.38) | KMT2AALDH1A1L3MBTL1HPGDHCAR2 | |
| SCHEMBL101243 | 0.85 | LMNA (0.41) | KMT2ATSHRALDH1A1L3MBTL1HCAR2 | |
| SCHEMBL102843 | 0.85 | HCAR2 (0.42) | HDAC1KMT2ATSHRHCAR2LMNA | |
| SCHEMBL102082 | 0.85 | RAB9A (0.44) | HCAR2 | |
| SCHEMBL98766 | 0.85 | LTB4R (0.52) | KMT2ATSHRALDH1A1HPGDHCAR2 | |
| SCHEMBL100652 | 0.85 | HCAR2 (0.44) | KMT2AHPGDHCAR2TRPV1MEN1 | |
| SCHEMBL100167 | 0.84 | SMN1; SMN2 (0.43) | HDAC1KMT2ATSHRALDH1A1HCAR2 | |
| SCHEMBL99078 | 0.84 | HCAR2 (0.42) | KMT2AALDH1A1HPGDHCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |