Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99669 | 0.95 | NPC1 (0.45) | RAB9APOLBHCAR2NPC1SMN1; SMN2 | |
| SCHEMBL101458 | 0.91 | HCAR2 (0.45) | RAB9APOLBHCAR2AKR1C3AKR1C2 | |
| SCHEMBL100652 | 0.90 | HCAR2 (0.44) | RAB9AHCAR2NPC1SMN1; SMN2AKR1C3 | |
| SCHEMBL102147 | 0.89 | LTB4R (0.44) | HCAR2SMN1; SMN2LTB4R | |
| SCHEMBL98766 | 0.88 | LTB4R (0.52) | POLBHCAR2SMN1; SMN2LTB4R | |
| SCHEMBL99813 | 0.87 | HCAR2 (0.44) | RAB9AHCAR2RORC | |
| SCHEMBL100524 | 0.85 | RORC (0.43) | RAB9AHCAR2NPC1SMN1; SMN2RORC | |
| SCHEMBL175770 | 0.85 | CHRM3 (0.49) | — | |
| SCHEMBL99078 | 0.85 | HCAR2 (0.42) | RAB9AHCAR2 | |
| SCHEMBL99712 | 0.85 | HDAC1 (0.40) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |