Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586811 | 0.93 | CTSB (0.47) | CTSBANPEPRNPEPDNPEPCTSK | |
| SCHEMBL8584909 | 0.89 | CTSB (0.44) | CTSBANPEPRNPEPDNPEPCTSK | |
| SCHEMBL3667251 | 0.89 | CTSK (0.42) | CTSBCTSKCTSSCTSLALDH1A1 | |
| SCHEMBL724546 | 0.88 | CTSK (0.46) | CTSBCTSKCTSSCTSLPSMB1 | |
| SCHEMBL8584242 | 0.87 | CTSL (0.44) | CTSBANPEPRNPEPDNPEPCTSK | |
| SCHEMBL19400126 | 0.84 | CTSK (0.56) | CTSBCTSKCTSSCTSLPSMB1 | |
| SCHEMBL26910148 | 0.84 | CTSK (0.56) | CTSBCTSKCTSSCTSLPSMB1 | |
| SCHEMBL28288627 | 0.84 | CTSK (0.56) | CTSBCTSKCTSSCTSLPSMB1 | |
| Hydrochloric Acid SCHEMBL11145585 | 0.83 | NPY4R (0.41) | CTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL7420644 | 0.82 | ANPEP (0.43) | CTSBANPEPRNPEPDNPEPCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9128081-B2 | TDP-43-storing cell model | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2015-09-08 | — | — | US | disclosed |
| EP-2272955-B1 | TDP-43-STORING CELL MODEL | TOKYO METROPOLITAN INST MEDICAL SCIENCE (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8715643-B2 | TDP-43-storing cell model | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2014-05-06 | — | — | US | disclosed |
| US-20140099660-A1 | TDP-43-STORING CELL MODEL | TOKYO METROPOLITIAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2014-04-10 | — | — | US | disclosed |
| US-20110034447-A1 | TDP-43-STORING CELL MODEL | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2272955-A1 | TDP-43-STORING CELL MODEL | Tokyo Metropolitan Organization for Medical Research (JP) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010034863-A1 | USE OF KINASE INHIBITORS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PARKINSON’S DISEASE, PHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC PROCEDURE FOR PARKINSON’S DISEASE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2010-04-01 | — | — | WO | disclosed |
| EP-1153612-A1 | ANTICANCER AGENT POTENTIATORS | Tsuruo, Takashi (US) | 2001-11-14 | — | — | EP | disclosed |