Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IL2 | P60568 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646105 | 0.86 | RAB9A (0.43) | RAB9ANPC1CYP1A2BRPF1MEN1 | |
| SCHEMBL10151679 | 0.83 | STIM1 (0.37) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL13108669 | 0.83 | MEN1 (0.40) | RAB9ANPC1CYP1A2MEN1KMT2A | |
| SCHEMBL10151674 | 0.82 | TP53 (0.38) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL10151409 | 0.82 | ALDH1A1 (0.40) | RAB9ANPC1KDM4EPOLBPPARG | |
| SCHEMBL3103400 | 0.81 | RAB9A (0.45) | RAB9ANPC1CYP1A2BRPF1MEN1 | |
| SCHEMBL3104227 | 0.80 | RAB9A (0.44) | RAB9ANPC1CYP1A2BRPF1MEN1 | |
| SCHEMBL647154 | 0.79 | RAB9A (0.43) | RAB9ANPC1CYP1A2BRPF1MEN1 | |
| SCHEMBL10151390 | 0.78 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL8069094 | 0.77 | STIM1 (0.43) | RAB9ANPC1CYP1A2BRPF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119643-B2 | Benzoimidazolyl-pyrazine compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP. (US) | 2012-02-21 | — | — | US | disclosed |