Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811503 | 0.98 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL102775 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL3811504 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL8345288 | 0.89 | CYP3A4 (0.56) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Ether SCHEMBL3811500 | 0.88 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL125981 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL1527142 | 0.87 | CYP3A4 (0.53) | ALDH1A1CYP3A4MMP9MMP8MMP14 | |
| Alcohol SCHEMBL2450700 | 0.85 | ALDH1A1 (0.60) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL29209616 | 0.83 | ALDH1A1 (0.72) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL8024375 | 0.83 | CYP3A4 (0.58) | ALDH1A1CYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402302-B1 | PROCESS FOR PRODUCING ETHER COMPOUND | KAO CORP (JP) | 2017-11-22 | — | — | EP | disclosed |
| US-8829229-B2 | Polyol ethers and process for making them | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2318346-B1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-2426099-A1 | Coalescent for aqueous compositions | Rohm and Haas Company (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20120052210-A1 | COALESCENT FOR AQUEOUS COMPOSITIONS | VAN DYK ANTONY KEITH (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120004470-A1 | PROCESS FOR PRODUCING ETHER COMPOUND | KAO CORPORATION (JP) | 2012-01-05 | — | — | US | disclosed |
| EP-2402302-A1 | PROCESS FOR PRODUCING ETHER COMPOUND | Kao Corporation (JP) | 2012-01-04 | — | — | EP | disclosed |
| WO-2011106194-A2 | PROCESS FOR MAKING POLYOL ETHERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20110207969-A1 | PROCESS FOR MAKING POLYOL ETHERS | DOW GLOBAL TECHNOLOGIES LLC | 2011-08-25 | — | — | US | disclosed |
| EP-2318346-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010027663-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207969-A1 | PROCESS FOR MAKING POLYOL ETHERS | PUF60, PARG, PCBP1 | ALDH1A1 3977/4885CYP3A4 277/4885TSHR 4862/4885 |
| US-20120004470-A1 | PROCESS FOR PRODUCING ETHER COMPOUND | CYP4F11, CYP4A11, RPS14 | ALDH1A1 2958/4885CYP3A4 34/4885TSHR 3761/4885 |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | RNF114, USP14, USP13 | ALDH1A1 692/4885CYP3A4 133/4885TSHR 3945/4885 |
| US-20120052210-A1 | COALESCENT FOR AQUEOUS COMPOSITIONS | DGAT2, DGAT1, DAGLB | ALDH1A1 3271/4885CYP3A4 2516/4885TSHR 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.