Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958824 | 0.92 | ALDH1A1 (0.44) | PRMT5WDR77MEN1KMT2AALDH1A1 | |
| SCHEMBL9959556 | 0.91 | PRMT5 (0.46) | PRMT5WDR77MEN1KMT2AALDH1A1 | |
| SCHEMBL9959530 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9959528 | 0.87 | L3MBTL1 (0.37) | PRMT5WDR77MEN1KMT2AALDH1A1 | |
| SCHEMBL9959313 | 0.85 | KCNA5 (0.48) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10153721 | 0.85 | KDR (0.47) | PRMT5WDR77LMNAMAPTL3MBTL1 | |
| SCHEMBL9960564 | 0.84 | TRPA1 (0.38) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10153600 | 0.82 | MAPT (0.44) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL9959558 | 0.82 | KCNA5 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL21074868 | 0.81 | ALDH1A1 (0.43) | PRMT5WDR77MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085003-A1 | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-06-28 | — | — | WO | disclosed |