SCHEMBL10158588

SCHEMBL10158588

CCC(C)(C)C(=O)OCC(C)(CO)CO

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
HMGCR P04035 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9924519 0.82 LMNA (0.37) CYP4F2CYP4A11LMNAHSD17B10HMGCR
SCHEMBL130762 0.80 CYP4F2 (0.38) CYP4F2CYP4A11LMNAHSD17B10HMGCR
SCHEMBL21284569 0.80 CYP4F2 (0.38) CYP4F2CYP4A11LMNAHSD17B10HMGCR
SCHEMBL17067673 0.80 CYP4F2 (0.37) CYP4F2CYP4A11LMNAHSD17B10KDM4E
SCHEMBL11991310 0.80 LMNA (0.33) CYP4F2CYP4A11LMNAHSD17B10
SCHEMBL6368436 0.78 CYP4F2 (0.37) CYP4F2CYP4A11LMNAHSD17B10HMGCR
SCHEMBL13301441 0.78 CYP4F2 (0.37) CYP4F2CYP4A11LMNAHSD17B10HMGCR
SCHEMBL1628655 0.78 CYP4F2 (0.44) CYP4F2CYP4A11LMNAHSD17B10KDM4E
SCHEMBL2179864 0.78 CYP4F2 (0.39) CYP4F2CYP4A11LMNAHSD17B10HMGCR
SCHEMBL10094796 0.77 CYP4F2 (0.38) CYP4F2CYP4A11LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150752-B2 Coating composition with trisamine functionalized dispersant DOW GLOBAL TECHNOLOGIES LLC (US) 2015-10-06 US disclosed
US-20150252213-A1 COATING COMPOSITION WITH TRISAMINE FUNCTIONALIZED DISPERSANT DOW GLOBAL TECHNOLOGIES LLC 2015-09-10 US disclosed
US-20130195954-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2013-08-01 US disclosed
US-20130195954-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2013-08-01 US disclosed
US-8338492-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-12-25 US disclosed
US-8334324-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-12-18 US disclosed
US-20120107365-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-05-03 US disclosed
US-20110152305-A1 FILMS AND PARTICLES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2011-06-23 US disclosed
US-7671095-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2010-03-02 US disclosed
US-20080075718-A1 Films and Particles THE TRUSTEES OF THE BOSTON UNIVERSITY 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152305-A1 FILMS AND PARTICLES APOB, PGF, ACTB CYP4F2 3742/4885CYP4A11 3623/4885LMNA 220/4885
US-20130195954-A1 FILMS AND PARTICLES APOB, PGF, ACTB CYP4F2 3742/4885CYP4A11 3623/4885LMNA 220/4885
US-20080075718-A1 Films and Particles APOB, PGF, ACTB CYP4F2 3742/4885CYP4A11 3623/4885LMNA 220/4885
US-20120107365-A1 FILMS AND PARTICLES APOB, PGF, ACTB CYP4F2 3742/4885CYP4A11 3623/4885LMNA 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.