Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832913 | 0.87 | NR1H3 (0.47) | NR1H3MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL17914398 | 0.86 | ACHE (0.50) | ALOX15HSD17B10HSD11B1PGK1PGK2 | |
| SCHEMBL10165224 | 0.86 | HSD11B1 (0.43) | NR1H3HSD11B1PGK1PGK2 | |
| SCHEMBL19734501 | 0.86 | ACHE (0.50) | NR1H3MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL24436844 | 0.84 | NR1H3 (0.44) | NR1H3MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL26548517 | 0.84 | NR1H3 (0.44) | NR1H3MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL13965655 | 0.83 | NR1H3 (0.48) | NR1H3NR1H2HSD11B1 | |
| SCHEMBL13965654 | 0.82 | PTPN5 (0.46) | HSD11B1 | |
| SCHEMBL29509593 | 0.81 | TSHR (0.50) | NR1H3MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL24901407 | 0.81 | TSHR (0.50) | NR1H3MEN1ALOX15TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457759-B2 | Co-delivery of cholesterol lowering drugs and nutraceuticals | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-10-29 | — | — | US | disclosed |
| US-20190023824-A1 | CO-DELIVERY OF CHOLESTEROL LOWERING DRUGS AND NUTRACEUTICALS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-01-24 | — | — | US | disclosed |
| US-9650451-B2 | Fluorine-containing compounds and their polymers useful for anti-reflection film materials and resist compositions | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-05-16 | — | — | US | disclosed |
| US-20170114183-A1 | METHODS OF FORMING BLOCK POLYMERS FOR DIRECTED SELF-ASSEMBLY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-04-27 | — | — | US | disclosed |
| US-8981163-B2 | Fluorine-containing aromatic compound and method for producing same | Centrall Glass Company, Limited (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140194655-A1 | Fluorine-Containing Aromatic Compound and Method for Producing Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20140171584-A1 | Fluorine-Containing Compounds and Their Polymers Useful for Anti-Reflection Film Materials and Resist Compositions | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-06-19 | — | — | US | disclosed |
| US-8410290-B2 | Cyclic carbonyl compounds with pendant carbonate groups, preparations thereof, and polymers therefrom | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-04-02 | — | — | US | disclosed |
| US-8389746-B2 | Cyclic carbonyl compounds with pendant carbonate groups, preparations thereof, and polymers therefrom | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-03-05 | — | — | US | disclosed |
| US-8361495-B2 | Antimicrobial polymers and methods of manufacture thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120252983-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | CENTRAL GLASS CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120245304-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | CENTRAL GLASS CO., LTD. (JP) | 2012-09-27 | — | — | US | disclosed |
| US-8207351-B2 | Cyclic carbonyl compounds with pendant carbonate groups, preparations thereof, and polymers therefrom | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| WO-2011135046-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT PENTAFLUOROPHENYL CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110269917-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | CENTRAL GLASS CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| WO-2011136872-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORP. (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110196121-A1 | Fluorine-Containing Compounds and their Polymers Useful for Anti-Reflection Film Materials and Resist Compositions | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-08-11 | — | — | US | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252983-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | NOTUM, PFAS, PCNA | NR1H3 4668/4885MEN1 3439/4885ALOX15 816/4885 |
| US-20110196121-A1 | Fluorine-Containing Compounds and their Polymers Useful for Anti-Reflection Film Materials and Resist Compositions | DNMT3B, DNMT3L, AFF1 | NR1H3 997/4885MEN1 885/4885ALOX15 2960/4885 |
| US-20140194655-A1 | Fluorine-Containing Aromatic Compound and Method for Producing Same | AFF1, AFF2, AFF4 | NR1H3 621/4885MEN1 170/4885ALOX15 3262/4885 |
| US-10457759-B2 | Co-delivery of cholesterol lowering drugs and nutraceuticals | STARD3, HMGCR, CETP | NR1H3 41/4885MEN1 4236/4885ALOX15 965/4885 |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | NR1H3 4633/4885MEN1 3094/4885ALOX15 1355/4885 |
| US-20190023824-A1 | CO-DELIVERY OF CHOLESTEROL LOWERING DRUGS AND NUTRACEUTICALS | STARD3, HMGCR, CETP | NR1H3 41/4885MEN1 4236/4885ALOX15 965/4885 |
| US-20110269917-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | NOTUM, PFAS, PCNA | NR1H3 4668/4885MEN1 3439/4885ALOX15 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.