SCHEMBL21550488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17051575	0.89	NPC1 (0.44)	NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1
	SCHEMBL10000239	0.82	NPC1 (0.53)	NPC1RAB9ASMN1; SMN2PAX8METAP2
	SCHEMBL17051572	0.80	NPC1 (0.52)	NPC1RAB9ASMN1; SMN2PAX8METAP2
	SCHEMBL10000247	0.80	NPC1 (0.52)	NPC1RAB9ASMN1; SMN2PAX8METAP2
	SCHEMBL23084949	0.78	MAPT (0.45)	NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1
	SCHEMBL17185269	0.78	METAP2 (0.39)	NPC1RAB9ASMN1; SMN2APPMETAP2
	SCHEMBL10165319	0.78	RAB9A (0.52)	NPC1RAB9ASMN1; SMN2RXFP1ALDH1A1
	SCHEMBL15888366	0.78	SLC6A2 (0.47)	NPC1RAB9ASMN1; SMN2ADORA2AADORA1
	SCHEMBL423171	0.77	RAB9A (0.55)	NPC1RAB9ASMN1; SMN2ADORA2AADORA1
	SCHEMBL17055375	0.76	RAB9A (0.53)	NPC1RAB9ASMN1; SMN2ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.