Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625030 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TDP1MMP1MMP2MMP3 | |
| SCHEMBL24221392 | 0.82 | HDAC7 (0.35) | TDP1TSHR | |
| SCHEMBL10166039 | 0.82 | HDAC7 (0.35) | TDP1TSHR | |
| SCHEMBL25777637 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL13213430 | 0.81 | TGFBR1 (0.34) | TDP1TSHR | |
| SCHEMBL12766316 | 0.81 | TGFBR1 (0.34) | TDP1TSHR | |
| SCHEMBL19361692 | 0.79 | TDP1 (0.30) | TDP1 | |
| SCHEMBL18932853 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHR | |
| SCHEMBL12766327 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MMP2 | |
| SCHEMBL24494714 | 0.79 | ACE (0.39) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024016071-A1 | RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-01-25 | — | — | WO | disclosed |
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | PROTOMER TECHNOLOGIES, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | PROTOMER TECHNOLOGIES, INC. | 2023-05-04 | — | — | US | disclosed |
| WO-2021217019-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-28 | — | — | WO | disclosed |
| US-20170144998-A1 | ELASTASE INHIBITORS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2017-05-25 | — | — | US | disclosed |
| US-9656972-B2 | Compounds for treatment of cystic fibrosis | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-05-23 | — | — | US | disclosed |
| US-20160159754-A1 | COMPOUNDS FOR TREATMENT OF CYSTIC FIBROSIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2016-06-09 | — | — | US | disclosed |
| US-9029359-B2 | Heteroaryl Btk inhibitors | BIOGEN IDEC MA, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20120157442-A1 | HETEROARYL BTK INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20100130581-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN | THE UNIVERSITY OF QUEENSLAND | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159754-A1 | COMPOUNDS FOR TREATMENT OF CYSTIC FIBROSIS | CFTR, ELANE, OTC | ALDH1A1 1108/4885TDP1 4703/4885MMP1 42/4885 |
| US-20120157442-A1 | HETEROARYL BTK INHIBITORS | BTK, LYN, SYK | ALDH1A1 4759/4885TDP1 810/4885MMP1 4782/4885 |
| US-20100130581-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN | OPRL1, CRH, OPRK1 | ALDH1A1 2824/4885TDP1 3975/4885MMP1 3090/4885 |
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | GPR119, GLP1R, IAPP | ALDH1A1 1361/4885TDP1 3729/4885MMP1 3189/4885 |
| US-20170144998-A1 | ELASTASE INHIBITORS | SERPINB1, ELANE, CELA1 | ALDH1A1 2088/4885TDP1 1042/4885MMP1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.