Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 15/20 | 0.58 |
| ▸ | ECE1 | P42892 | 3/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464865 | 0.91 | NPY4R (0.61) | KISS1RECE1ERAP2 | |
| SCHEMBL10168837 | 0.89 | ECE1 (0.62) | KISS1RECE1 | |
| SCHEMBL30464857 | 0.88 | NPY4R (0.61) | KISS1RECE1 | |
| SCHEMBL30436748 | 0.88 | KISS1R (0.60) | KISS1RECE1 | |
| SCHEMBL14685610 | 0.88 | KISS1R (0.62) | KISS1RECE1 | |
| SCHEMBL3497693 | 0.87 | KISS1R (0.62) | KISS1RECE1 | |
| SCHEMBL29825066 | 0.86 | NPY4R (0.61) | KISS1R | |
| SCHEMBL15896272 | 0.84 | ECE1 (0.61) | KISS1RECE1ERAP2IL1RN | |
| SCHEMBL29794137 | 0.84 | GHSR (0.57) | KISS1RECE1 | |
| Glycine SCHEMBL3497691 | 0.84 | KISS1R (0.58) | KISS1RECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | APLNR, AP1G1, AP2B1 | KISS1R 1243/4885ECE1 2459/4885ERAP2 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.