Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389425 | 0.93 | GPR119 (1.00) | GPR119CYP3A4 | |
| SCHEMBL10170747 | 0.89 | GPR119 (0.86) | GPR119 | |
| SCHEMBL386936 | 0.88 | GPR119 (0.90) | GPR119CYP3A4 | |
| SCHEMBL14788759 | 0.84 | GPR119 (0.78) | GPR119 | |
| SCHEMBL27769056 | 0.84 | GPR119 (0.83) | GPR119 | |
| SCHEMBL390398 | 0.83 | GPR119 (1.00) | GPR119CYP3A4 | |
| SCHEMBL3495404 | 0.82 | GPR119 (0.78) | GPR119 | |
| SCHEMBL390325 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL386232 | 0.82 | GPR119 (0.81) | GPR119CYP3A4 | |
| SCHEMBL389690 | 0.81 | GPR119 (1.00) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
| US-20120052130-A1 | GPR 119 MODULATORS | PFIZER INC. | 2012-03-01 | — | — | US | disclosed |
| US-20110020460-A1 | GPR 119 MODULATORS | PFIZER INC. | 2011-01-27 | — | — | US | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052130-A1 | GPR 119 MODULATORS | GPR119, GPR39, GPR65 | GPR119 1/4885CYP3A4 1837/4885 |
| US-20100285145-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | GPR119 1/4885CYP3A4 2077/4885 |
| US-20110020460-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR88 | GPR119 1/4885CYP3A4 2087/4885 |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | GPR3, GPR119, GPR84 | GPR119 2/4885CYP3A4 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.