SCHEMBL1017452

SCHEMBL1017452

Oc1ccc2c(c1)CCNC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.62
DRD1 P21728 2/20 0.62
ASIC3 Q9UHC3 2/20 0.60
DRD3 P35462 2/20 0.56
DRD4 P21917 2/20 0.56
DRD5 P21918 1/20 0.56
PNMT P11086 4/20 0.55
CD44 P16070 1/20 0.54
MAOB P27338 1/20 0.54
ADRA2A P08913 1/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
ADCY6 O43306 1/20 0.50
ADCY3 O60266 1/20 0.50
ADCY9 O60503 1/20 0.50
ADCY5 O95622 1/20 0.50
ADCY8 P40145 1/20 0.50
ADCY7 P51828 1/20 0.50
ADCY2 Q08462 1/20 0.50
ADCY1 Q08828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29514775 1.00 DRD2 (0.62) DRD2DRD1ASIC3DRD3DRD4
Hydrochloric Acid SCHEMBL453336 0.98 DRD2 (0.61) DRD2DRD1ASIC3DRD3DRD4
Bromide SCHEMBL587893 0.98 DRD2 (0.61) DRD2DRD1ASIC3DRD3DRD4
Hydrochloric Acid SCHEMBL31336072 0.98 DRD2 (0.61) DRD2DRD1ASIC3DRD3DRD4
SCHEMBL470826 0.92 PNMT (0.66) DRD2DRD1DRD3DRD4DRD5
Oxalic Acid SCHEMBL6952790 0.91 DRD2 (0.54) DRD2DRD1ASIC3DRD3DRD4
Hydrochloric Acid SCHEMBL2675120 0.90 PNMT (0.63) DRD2DRD1DRD3DRD4DRD5
Bromide SCHEMBL6190676 0.90 PNMT (0.63) DRD2DRD1DRD3DRD4DRD5
Hydrochloric Acid SCHEMBL30955057 0.90 PNMT (0.63) DRD2DRD1DRD3DRD4DRD5
SCHEMBL3694554 0.88 DRD2 (0.61) DRD2DRD1ASIC3DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119685827-B Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2026-05-12 CN claimed
CN-119685827-A Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2025-03-25 CN claimed
EP-1831173-A1 TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS JANSSEN PHARMACEUTICA N.V. (BE) 2007-09-12 EP claimed
WO-2006066197-A1 TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS JANSSEN PHARMACEUTICA, N.V. (BE) 2006-06-22 WO claimed
CN-119685827-B Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2026-05-12 CN disclosed
US-20260116923-A1 CYCLIC PEPTIDE IL-1BETA TRAP FOR THE TREATMENT OF ATHEROSCLEROSIS AND INFLAMMATORY DISORDERS MERCK SHARP & DOHME LLC (US) 2026-04-30 US disclosed
US-20250282781-A1 APOL1 INHIBITORS AND METHODS OF USE HERCULES CAPITAL, INC., AS AGENT 2025-09-11 US disclosed
US-12344610-B2 APOL1 inhibitors and methods of use MAZE THERAPEUTICS, INC. (US) 2025-07-01 US disclosed
CN-120040420-A Heterocyclic-pyrazole amine derivatives, preparation method thereof and application thereof in resisting tubercle bacillus infection 中国医学科学院医药生物技术研究所 2025-05-27 CN disclosed
WO-2025101738-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE PRELUDE THERAPEUTICS INCORPORATED (US) 2025-05-15 WO disclosed
CN-119685827-A Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2025-03-25 CN disclosed
WO-2024249254-A2 METHODS OF USING APOL1 INHIBITORS MAZE THERAPEUTICS, INC. (US) 2024-12-05 WO disclosed
EP-0992502-A1 2-(3-Phenyl-2-propenyl)-1,2,3,4-tetrahydro-isochinolin derivatives, process for their preparation and their use as fungicides HOECHST MARION ROUSSEL (FR) 2000-04-12 EP disclosed
US-5912342-A SYNTHESIS OF COMBINATORIAL LIBRARIES BY COMPUTER CONTROLLED ROBOT HEINONEN PETRI (FI) 1999-06-15 US disclosed
EP-0687267-A1 PYRROLO-PYRIDINE DERIVATIVES MERCK SHARP & DOHME LTD. (GB) 1995-12-20 EP disclosed
EP-0641324-A1 TETRAHYDRO AND PERHYDRO ISOQUINOLIN DERIVATIVES AND THERAPEUTIC AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1995-03-08 EP disclosed
CN-1085214-A Tetrahydrochysene one and perhydro isoquinilone derivatives and the therapeutic composition that contains these compounds BASF AG (DE) 1994-04-13 CN disclosed
WO-1993024461-A1 TETRAHYDRO AND PERHYDRO ISOQUINOLIN DERIVATIVES AND THERAPEUTIC AGENTS CONTAINING THEM BASF AKTIENGESELLSCHAFT (DE) 1993-12-09 WO disclosed
US-4717724-A FUNGICIDES, ANTIPROTOZOA, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-05 US disclosed
EP-0121753-A2 1-(1,3-Dioxolan-2-ylmethyl)-azoles, their salts, processes for their preparation and pharmaceutical compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344610-B2 APOL1 inhibitors and methods of use APOL1, APOB, PON1 DRD2 4503/4885DRD1 3228/4885ASIC3 4591/4885
US-20260116923-A1 CYCLIC PEPTIDE IL-1BETA TRAP FOR THE TREATMENT OF ATHEROSCLEROSIS AND INFLAMMATORY DISORDERS IL1A, IL1B, IL1RN DRD2 4501/4885DRD1 4210/4885ASIC3 3511/4885
US-20250282781-A1 APOL1 INHIBITORS AND METHODS OF USE APOL1, APOB, PON1 DRD2 4503/4885DRD1 3228/4885ASIC3 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.