Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 6/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962948 | 0.88 | ACMSD (0.46) | FABP4PTGS1AKR1C3AKR1C2SIRT2 | |
| SCHEMBL22453284 | 0.84 | SIRT2 (0.60) | SIRT2MEN1KMT2AALDH1A1SERPINE1 | |
| SCHEMBL22452463 | 0.82 | DHODH (0.46) | FABP4PTGS1AKR1C3AKR1C2MEN1 | |
| SCHEMBL15178352 | 0.82 | KMT2A (0.41) | FABP4SIRT2MEN1KMT2AALDH1A1 | |
| SCHEMBL18109767 | 0.81 | FABP4 (0.85) | FABP4PTGS1AKR1C3AKR1C2SIRT2 | |
| SCHEMBL7841736 | 0.78 | FABP4 (0.85) | FABP4PTGS1AKR1C3AKR1C2SIRT2 | |
| SCHEMBL1335958 | 0.78 | NPY5R (0.60) | PTGS1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11199863 | 0.78 | NPY5R (0.60) | PTGS1MEN1KMT2AALDH1A1MAPT | |
| Fenamic Acid SCHEMBL25828 | 0.78 | FABP4 (0.92) | FABP4PTGS1AKR1C3AKR1C2MEN1 | |
| Fenamic Acid SCHEMBL29622832 | 0.78 | FABP4 (0.92) | FABP4PTGS1AKR1C3AKR1C2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | GPR35, GPR65, GPR68 | FABP4 501/4885PTGS1 802/4885AKR1C3 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.