Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178711 | 0.89 | PLA2G4B (0.37) | LMNATSHRHSD17B10 | |
| SCHEMBL10180281 | 0.87 | PLA2G4B (0.39) | TSHRHSD17B10 | |
| SCHEMBL13260890 | 0.86 | ADRA2A (0.50) | ADRA2AADRA1AMAPTBLMACHE | |
| SCHEMBL10180339 | 0.83 | DNM1 (0.48) | MAPTBLMCYP2C19CHRM5CHRM1 | |
| SCHEMBL10178769 | 0.82 | DGKA (0.40) | MAPTLMNATSHRHSD17B10 | |
| SCHEMBL10180372 | 0.80 | CYP1A2 (0.44) | MAPTCYP2C19L3MBTL1PGRLMNA | |
| SCHEMBL10178811 | 0.80 | TSHR (0.39) | L3MBTL1LMNATSHRRAB9AHSD17B10 | |
| SCHEMBL3421547 | 0.80 | PDE1A (0.39) | HSD17B10 | |
| SCHEMBL10178886 | 0.80 | HSD17B10 (0.37) | HSD17B10 | |
| SCHEMBL10178984 | 0.80 | TSHR (0.32) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-7723409-B2 | Coupling agents between filler and elastomer | CIBA SPECIALTY CHEM. CORP. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080287578-A1 | Coupling Agents Between Filler and Elastomer | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | ADRA2A 2558/4885ADRA1A 1641/4885MAPT 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.