Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178711 | 0.86 | PLA2G4B (0.37) | DGKAHSD17B10PLA2G4BEPHX2LMNA | |
| SCHEMBL10180281 | 0.85 | PLA2G4B (0.39) | DGKAHSD17B10PLA2G4BEPHX2TSHR | |
| SCHEMBL10178886 | 0.85 | HSD17B10 (0.37) | DGKAHSD17B10 | |
| SCHEMBL10338675 | 0.85 | DGKA (0.53) | DGKAHSD17B10PLA2G4BEPHX2ALDH1A1 | |
| SCHEMBL10178702 | 0.82 | ADRA2A (0.47) | HSD17B10LMNATSHRMAPT | |
| SCHEMBL29392202 | 0.81 | DGKA (0.60) | DGKAEPHX2LMNAALDH1A1TSHR | |
| SCHEMBL10180339 | 0.81 | DNM1 (0.48) | DGKAHSD17B10PLA2G4BALDH1A1TSHR | |
| SCHEMBL23243665 | 0.79 | DGKA (0.59) | DGKAHSD17B10PLA2G4BEPHX2MAPT | |
| SCHEMBL10178960 | 0.78 | PLA2G4B (0.45) | HSD17B10PLA2G4BLMNAALDH1A1TSHR | |
| SCHEMBL9074502 | 0.78 | DGKA (0.54) | DGKAHSD17B10PLA2G4BEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-7723409-B2 | Coupling agents between filler and elastomer | CIBA SPECIALTY CHEM. CORP. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080287578-A1 | Coupling Agents Between Filler and Elastomer | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | DGKA 2569/4885HSD17B10 2353/4885PLA2G4B 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.