Sugi Predict

Sugi Predict / Compounds / SCHEMBL1018549

SCHEMBL1018549

SCHEMBL1018549

CCN(CC)C(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 6/20 0.61
▸ ALDH1A1 P00352 4/20 0.61
▸ MAPT P10636 2/20 0.61
▸ MLYCD O95822 1/20 0.59
▸ LMNA P02545 3/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ HSP90AA1 P07900 5/20 0.53
▸ HSP90AB1 P08238 5/20 0.53
▸ RAB9A P51151 2/20 0.50
▸ PARP10 Q53GL7 1/20 0.50
▸ OPRM1 P35372 1/20 0.50
▸ OPRD1 P41143 1/20 0.50
▸ OPRK1 P41145 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ CYP1A2 P05177 1/20 0.49
▸ BLM P54132 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5703500 0.89 HPGD (0.73) HPGDALDH1A1MAPTMLYCDLMNA
SCHEMBL28278838 0.84 MLYCD (0.62) HPGDALDH1A1MAPTMLYCDSMN1; SMN2
SCHEMBL7314304 0.83 HSP90AA1 (0.54) HPGDALDH1A1MAPTMLYCDLMNA
SCHEMBL3081053 0.83 HPGD (0.61) HPGDALDH1A1MAPTMLYCDLMNA
SCHEMBL31295694 0.82 OPRD1 (0.46) HPGDALDH1A1MAPTMLYCDMEN1
SCHEMBL8755196 0.81 EGFR (0.60) HPGDALDH1A1MLYCDMEN1KMT2A
SCHEMBL2854780 0.81 HPGD (0.67) HPGDALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL5316538 0.81 PARP10 (0.45) HPGDALDH1A1MAPTMLYCDKMT2A
SCHEMBL6802252 0.81 HPGD (0.69) HPGDALDH1A1MAPTMLYCDLMNA
SCHEMBL121475 0.81 HPGD (0.66) HPGDALDH1A1MAPTMLYCDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621088-B Preparation method of diethyl terephthalamide 安徽新秀化学股份有限公司 2023-12-01 — — CN claimed
US-20100234377-A1 PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE EVOTEC AG (DE) 2010-09-16 — — US claimed
EP-2150532-A1 PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE Evotec AG (DE) 2010-02-10 — — EP claimed
WO-2008122787-A1 PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE EVOTEC AG (DE) 2008-10-16 — — WO claimed
EP-0418013-A2 Direct magnesiation of organic materials ARCH DEVELOPMENT CORPORATION (US) 1991-03-20 — — EP claimed
CN-114621088-B Preparation method of diethyl terephthalamide 安徽新秀化学股份有限公司 2023-12-01 — — CN disclosed
CN-114621088-B Preparation method of diethyl terephthalamide 安徽新秀化学股份有限公司 2023-12-01 — — CN disclosed
CN-114621088-B Preparation method of diethyl terephthalamide 安徽新秀化学股份有限公司 2023-12-01 — — CN disclosed
CN-114621088-A Preparation method of diethyl p-xylylene diacrylate 萧县新秀新材料有限公司 2022-06-14 — — CN disclosed
EP-3864119-A1 LIQUID COMPOSITION WITH DIHYDROXYTEREPHTHALIC ACID DIAMIDE COMPOUND WITH A HIGH SURFACTANT QUANTITY Henkel AG & Co. KGaA (DE) 2021-08-18 — — EP disclosed
CN-105037426-A Reactive type intumescent flame retardant and synthesis method thereof UNIV XUCHANG 2015-11-11 — — CN disclosed
US-20120094980-A1 PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING GUNZNER JANET L (US) 2012-04-19 — — US disclosed
EP-2150532-A1 PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE Evotec AG (DE) 2010-02-10 — — EP disclosed
US-20090252013-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-08 — — US disclosed
WO-2008122787-A1 PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE EVOTEC AG (DE) 2008-10-16 — — WO disclosed
EP-0523470-B1 Complexed hydroquinones POLAROID CORP (US) 1997-03-19 — — EP disclosed
US-5338644-A Form complexes with N,N,N*,N*-tetrasubstituted diamides of aromatic dicarboxylic acids to prevent migration of hydroquinones puring storage POLAROID CORPORATION (US) 1994-08-16 — — US disclosed
EP-0523470-A2 Complexed hydroquinones POLAROID CORPORATION (US) 1993-01-20 — — EP disclosed
US-5177262-A Hydrogen-Bonded Complex with N,N,N',N'-Tetrasubstituted P-Aromatic Dicarboxamides POLAROID CORPORATION (US) 1993-01-05 — — US disclosed
EP-0418013-A2 Direct magnesiation of organic materials ARCH DEVELOPMENT CORPORATION (US) 1991-03-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234377-A1 PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE HPGDS, PTGDR, PTGIS HPGD 8/4885ALDH1A1 614/4885MAPT 4774/4885
US-20120094980-A1 PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING SHH, GLI1, SMO HPGD 2728/4885ALDH1A1 2407/4885MAPT 3822/4885
US-20090252013-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF KCNN2, KCNH2, KCNN1 HPGD 1847/4885ALDH1A1 1012/4885MAPT 1403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.