Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186470 | 0.88 | DGAT1 (0.44) | DGAT1MMP12HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL10185689 | 0.87 | MMP12 (0.53) | DGAT1MMP12ALDH1A1HSD17B10LMNA | |
| SCHEMBL10185044 | 0.87 | LMNA (0.54) | DGAT1HRH3L3MBTL1LMNAPOLB | |
| SCHEMBL10184403 | 0.85 | DGAT1 (0.54) | DGAT1HRH3ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL10184950 | 0.84 | DGAT1 (0.46) | DGAT1MMP12HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL10185270 | 0.84 | MMP13 (0.57) | DGAT1HRH3L3MBTL1HTTLMNA | |
| SCHEMBL10185040 | 0.83 | HDAC1 (0.46) | DGAT1HRH3OPRM1 | |
| SCHEMBL10185204 | 0.83 | ACSL1 (0.49) | DGAT1LMNAMEN1KMT2APOLB | |
| SCHEMBL10186411 | 0.83 | ALDH1A1 (0.55) | DGAT1ALDH1A1L3MBTL1HTTHSD17B10 | |
| SCHEMBL10185461 | 0.83 | DGAT1 (0.46) | DGAT1HRH3ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | DGAT1 1/4885MMP12 1217/4885HRH3 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.