SCHEMBL10187249

SCHEMBL10187249

Brc1nc2ccc3nc(Br)sc3c2s1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.32
NPC1 O15118 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17839739 0.79 PLK4 (0.30)
SCHEMBL1638399 0.76 CCNE1 (0.45)
SCHEMBL5419829 0.75 ALDH1A1 (0.41) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL18791158 0.74 PSMB8 (0.58) SMN1; SMN2ALDH1A1MAPTTDP1
SCHEMBL15881078 0.73 RAB9A (0.58) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL15880354 0.73 CLK1 (0.36) RAB9ANPC1ALDH1A1TDP1KDM4E
SCHEMBL11331664 0.72 TYMS (0.43) SMN1; SMN2ALDH1A1MAPTTDP1HTT
SCHEMBL11106009 0.71 LIPG (0.38) SMN1; SMN2ALDH1A1TDP1KDM4EHTT
SCHEMBL24820021 0.70 HDAC3 (0.44) RAB9ANPC1ALDH1A1
SCHEMBL19783341 0.70 KMT2A (0.36) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2630179-B1 CONJUGATED POLYMERS RAYNERGY TEK INC (TW) 2021-04-14 EP disclosed
US-9570688-B2 Semiconductor materials prepared from bridged bithiazole copolymers BASF SE (DE) 2017-02-14 US disclosed
US-9570688-B2 Semiconductor materials prepared from bridged bithiazole copolymers BASF SE (DE) 2017-02-14 US disclosed
US-9559303-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2017-01-31 US disclosed
EP-2601236-B1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COPOLYMERS BASF SE (DE) 2016-11-02 EP disclosed
US-20150162546-A1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COMPOLYERS BASF SE (DE) 2015-06-11 US disclosed
US-20150162546-A1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COMPOLYERS BASF SE (DE) 2015-06-11 US disclosed
US-20130214208-A1 Conjugated Polymers MERCK PATENT GMBH (DE) 2013-08-22 US disclosed
US-20130144065-A1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COPOLYMERS POLYERA CORPORATION (US) 2013-06-06 US disclosed
US-20130144065-A1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COPOLYMERS POLYERA CORPORATION (US) 2013-06-06 US disclosed
WO-2012016925-A2 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COPOLYMERS BASF SE (DE) 2012-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150162546-A1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COMPOLYERS CBS, SULT1A1, GSTA1 RAB9A 3942/4885NPC1 1436/4885SMN1; SMN2 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.