Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.59 |
| ▸ | CYBB | P04839 | 1/20 | 0.59 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.59 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.59 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998043 | 0.84 | NOX1 (0.56) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL7690724 | 0.80 | MAPT (0.58) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL23059883 | 0.80 | NOX1 (0.69) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| Phenothiazine SCHEMBL6532335 | 0.75 | NOX1 (1.00) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL560225 | 0.75 | NOX1 (1.00) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL29475150 | 0.75 | NOX1 (1.00) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL10193003 | 0.74 | NOX1 (0.56) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| Benzene SCHEMBL29242186 | 0.73 | NOX1 (0.97) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL11375009 | 0.71 | NOX1 (0.69) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL6999835 | 0.71 | NOX1 (0.56) | MAPTALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178077-B2 | Drug development target protein and target gene, and method of screening | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178077-B2 | Drug development target protein and target gene, and method of screening | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | REVERSE PROTEOMICS RESEARCH INSTITUTE CO. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | REVERSE PROTEOMICS RESEARCH INSTITUTE CO. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | NCS1, PRSS12, TPX2 | MAPT 214/4885ALDH1A1 4286/4885HPGD 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.