SCHEMBL1019608

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1022444	0.80	HTR6 (0.41)	HTR6HTR2CHTR2BTAAR1ALDH1A1
	SCHEMBL1020993	0.76	ALDH1A1 (0.50)	HTR6IDO1ADORA2AADORA1TAAR1
	SCHEMBL1021419	0.75	RAB9A (0.45)	TP53SMN1; SMN2ALDH1A1MEN1KMT2A
	SCHEMBL31551157	0.74	L3MBTL1 (0.33)	SMN1; SMN2NPSR1ALDH1A1MEN1KMT2A
	SCHEMBL1019884	0.73	HTR6 (0.38)	TP53SMN1; SMN2HTR6HTR2CHTR2B
	SCHEMBL17101949	0.72	MPO (0.36)	ADORA2AALDH1A1L3MBTL1NPC1HTT
	SCHEMBL1021044	0.72	TAAR1 (0.46)	TP53SMN1; SMN2HTR6HTR2CHTR2B
	SCHEMBL1019764	0.71	AOC3 (0.40)	HTR6HTR2CHTR2BNPSR1ADORA2A
	SCHEMBL2006686	0.71	HTR2B (0.46)	HTR6HTR2CHTR2BNPSR1ALDH1A1
	SCHEMBL1021187	0.71	TLR8 (0.38)	HTR6HTR2CHTR2BIDO1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.