Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707980 | 1.00 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL1815167 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL11222667 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL11582938 | 0.84 | L3MBTL1 (0.50) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL8565803 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL6270142 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL29853644 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| Hydrochloric Acid SCHEMBL10767073 | 0.82 | L3MBTL1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL34766 | 0.82 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL3527141 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304368-B | Composition of sodium hyaluronate and collagen pentapeptide and application thereof | 杭州湃肽生化科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-105777669-B | The method that 2 ethyoxyl 5 (the base sulfonyl of 4 methyl piperazine 1) benzoic acid are prepared with gaultherolin | 锦州医科大学 | 2018-03-20 | — | — | CN | claimed |
| CN-105777669-A | Method for preparing 2-ethyoxyl-5-(4-methyl piperazine-1-sulfonyl) benzoic acid from methyl salicylate | 锦州医科大学 | 2016-07-20 | — | — | CN | claimed |
| EP-2024369-A2 | NOVEL PROCESS FOR THE PREPARATION OF SILDENAFIL CITRATE | Matrix Laboratories Ltd (IN) | 2009-02-18 | — | — | EP | claimed |
| WO-2007141805-A2 | NOVEL PROCESS FOR THE PREPARATION OF SILDENAFIL CITRATE | MATRIX LABORATORIES LIMITED (IN) | 2007-12-13 | — | — | WO | claimed |
| CN-121948864-A | Modified manganese slag and application thereof in preparation of cement material | 湖南省耕地与农业环境生态研究所 | 2026-05-01 | — | — | CN | disclosed |
| US-12576055-B2 | Disease detection and treatment based on trimethyl-lysine levels | THE CLEVELAND CLINIC FOUNDATION (US) | 2026-03-17 | — | — | US | disclosed |
| WO-2024243289-A2 | GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-11-28 | — | — | WO | disclosed |
| US-20240165131-A1 | TREATING AND PREVENTING DISEASE WITH TMA AND TMAO LOWERING AGENTS | THE CLEVELAND CLINIC FOUNDATION | 2024-05-23 | — | — | US | disclosed |
| US-20240139120-A1 | TREATING DISEASE AND PROMOTING WEIGHT LOSS BY INHIBITING THE TMA/FMO3/TMAO PATHWAY | THE CLEVELAND CLINIC FOUNDATION | 2024-05-02 | — | — | US | disclosed |
| CN-117304368-B | Composition of sodium hyaluronate and collagen pentapeptide and application thereof | 杭州湃肽生化科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-11911399-B2 | Treating and preventing disease with TMA and TMAO lowering agents | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-5958911-A | ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-09-28 | — | — | US | disclosed |
| US-4939132-A | Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0198366-B1 | NOVEL 5-ALKYLSULFONYLSALICYLANLIDES AND MICROBIOCIDAL COMPOSITIONS FOR CONTROLLING THE GROWTH OF MICROORGANISMS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-09 | — | — | EP | disclosed |
| EP-0198366-A1 | Novel 5-alkylsulfonylsalicylanlides and microbiocidal compositions for controlling the growth of microorganisms | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4493885-A | DIFFUSION TRANSFER | FUJI PHOTO FILM CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4339455-A | 1-(3-Pyridyl)-2,2,2-trihaloethyl compounds and fungicidal compositions containing the same | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4189486-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-02-19 | — | — | US | disclosed |
| US-3943154-A | PLANT AND ANIMAL GROWTH REGULATORS | SANITIZED INCORPORATED (US) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11911399-B2 | Treating and preventing disease with TMA and TMAO lowering agents | MAOB, DAO, ESD | ALDH1A1 239/4885KDM4E 1290/4885HSD17B10 402/4885 |
| US-20240139120-A1 | TREATING DISEASE AND PROMOTING WEIGHT LOSS BY INHIBITING THE TMA/FMO3/TMAO PATHWAY | SLC5A2, SLC5A1, MAT1A | ALDH1A1 1973/4885KDM4E 2023/4885HSD17B10 713/4885 |
| US-12576055-B2 | Disease detection and treatment based on trimethyl-lysine levels | BHMT, BHMT2, EHMT2 | ALDH1A1 1296/4885KDM4E 270/4885HSD17B10 2588/4885 |
| US-20240165131-A1 | TREATING AND PREVENTING DISEASE WITH TMA AND TMAO LOWERING AGENTS | MAOB, DAO, ESD | ALDH1A1 239/4885KDM4E 1290/4885HSD17B10 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.