Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KIF11 | P52732 | 17/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843685 | 0.84 | ALOX15 (0.59) | CYP3A4ALOX15HSD17B10KIF11 | |
| SCHEMBL1025296 | 0.84 | ALDH1A1 (0.50) | CYP3A4ALOX15HSD17B10KIF11 | |
| SCHEMBL6823132 | 0.84 | ALDH1A1 (0.50) | CYP3A4ALOX15HSD17B10KIF11 | |
| SCHEMBL30313807 | 0.83 | ALOX15 (0.94) | CYP3A4ALOX15HSD17B10 | |
| SCHEMBL20945278 | 0.83 | ALOX15 (0.94) | CYP3A4ALOX15HSD17B10 | |
| SCHEMBL3903661 | 0.82 | KIF11 (0.61) | KIF11HDAC2 | |
| SCHEMBL23924225 | 0.81 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10 | |
| SCHEMBL29365557 | 0.81 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10 | |
| SCHEMBL105866 | 0.81 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10 | |
| SCHEMBL29549758 | 0.81 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | claimed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | claimed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | claimed |
| CN-115124485-B | Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-115697977-A | Benzopyrrole derivative and organic electroluminescent element comprising same | 株式会社乐普拓 | 2023-02-03 | — | — | CN | disclosed |
| CN-115124485-A | Benzoxazole derivatives containing sulfoxide as well as preparation method and application thereof | 中国医学科学院药物研究所 | 2022-09-30 | — | — | CN | disclosed |
| EP-1706111-A4 | COMPOUNDS, COMPOSITIONS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
| EP-1874753-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20070265345-A1 | Novel Biphenyl Compounds And Their Use | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070142460-A1 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED | 2007-06-21 | — | — | US | disclosed |
| EP-1778214-A2 | NOVEL BIPHENYL COMPOUNDS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006113432-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | disclosed |
| EP-1706111-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2006020358-A2 | NOVEL BIPHENYL COMPOUNDS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| WO-2005062847-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265345-A1 | Novel Biphenyl Compounds And Their Use | KIF5B, KIF5C, KIF5A | CYP3A4 2663/4885ALOX15 4599/4885HSD17B10 1127/4885 |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | CYP3A4 4722/4885ALOX15 2439/4885HSD17B10 1226/4885 |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | CYP3A4 835/4885ALOX15 3006/4885HSD17B10 913/4885 |
| US-20070142460-A1 | Compounds, compositions and methods | ALPP, PCNA, MKI67 | CYP3A4 4658/4885ALOX15 2250/4885HSD17B10 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.