Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 13/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TLR4 | O00206 | 1/20 | 0.55 |
| ▸ | TLR2 | O60603 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | ABL2 | P42684 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219463 | 1.00 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL28528161 | 1.00 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL6910815 | 0.89 | FBP1 (0.78) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL6910818 | 0.89 | FBP1 (0.78) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL5924031 | 0.78 | FBP1 (0.67) | FBP1EGFRTLR4TLR2ABL1 | |
| SCHEMBL2077031 | 0.78 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL421633 | 0.78 | FBP1 (0.64) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL102630 | 0.78 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL366121 | 0.78 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL1681205 | 0.78 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195646-B | Preparation method of 1-chloro-4- (6-nitrocyclohex-3-enyl) -benzene | 湖南化工研究院有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-112250581-B | Preparation method of trans-4-chloro-beta-nitrostyrene | 湖南海利常德农药化工有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-114195646-A | Preparation method of 1-chloro-4- (6-nitrocyclohex-3-enyl) -benzene | 湖南化工研究院有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-111116613-B | Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof | 湘潭大学 | 2021-04-23 | — | — | CN | claimed |
| CN-112250581-A | Preparation method of trans-4-chloro-beta-nitrostyrene | 湖南海利常德农药化工有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-104277072-B | A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives | JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104277072-A | Method for preparing (E)-2-aryl vinyl phosphonate derivatives | CHINASUN SPECIALTY PRODUCTS CO LTD | 2015-01-14 | — | — | CN | claimed |
| EP-2174927-B1 | METHOD FOR PRODUCING BETA-NITROSTYRENE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2013-09-11 | — | — | EP | claimed |
| CN-101765579-B | Method for producing beta-nitrostyrene compound | SUMITOMO CHEMICAL CO | 2013-08-28 | — | — | CN | claimed |
| CN-101628904-B | Synthesis method of 2-nitro-3-aryl-2,3,5,7-tetrahydrobenzofuran-4-one derivative | UNIV SOOCHOW | 2012-04-25 | — | — | CN | claimed |
| CN-101343263-B | Method for synthesizing 5-nitro-4, 5-dihydrofuran derivative | UNIV SOOCHOW | 2012-04-04 | — | — | CN | claimed |
| US-8067647-B2 | Method for producing β-nitrostyrene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | claimed |
| CN-101765579-A | Method for producing beta-nitrostyrene compound | SUMITOMO CHEMICAL CO | 2010-06-30 | — | — | CN | claimed |
| US-20100130795-A1 | METHOD FOR PRODUCING BETA-NITROSTYRENE COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED | 2010-05-27 | — | — | US | claimed |
| EP-2174927-A1 | METHOD FOR PRODUCING BETA-NITROSTYRENE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | claimed |
| CN-101628904-A | Synthesis method of 2-nitro-3-aryl-2,3,5,7-tetrahydrobenzofuran-4-one derivative | UNIV SOOCHOW | 2010-01-20 | — | — | CN | claimed |
| CN-101343263-A | Method for synthesis of 5-nitryl-4, 5-dihydrofuran derivant | UNIV SOOCHOW (CN) | 2009-01-14 | — | — | CN | claimed |
| EP-4651954-A1 | INHIBITORS OF MPTP | NRG Therapeutics LTD (GB) | 2025-11-26 | — | — | EP | disclosed |
| EP-0138030-A2 | Phenylethylamine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-3931220-A | FUNGICIDE, BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130795-A1 | METHOD FOR PRODUCING BETA-NITROSTYRENE COMPOUND | NAT1, NOS1, NOS2 | FBP1 2111/4885EGFR 4069/4885ALDH1A1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.