Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 12/20 | 0.82 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.76 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenamic Acid SCHEMBL17497 | 0.88 | RXFP1 (0.75) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| Flufenamic Acid SCHEMBL29356958 | 0.88 | RXFP1 (0.75) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| Flufenamic Acid SCHEMBL11524554 | 0.87 | RXFP1 (0.73) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| Flufenamic Acid SCHEMBL9845499 | 0.87 | RXFP1 (0.73) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| SCHEMBL4245559 | 0.86 | MAPK8 (0.67) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| SCHEMBL28133218 | 0.83 | FABP4 (0.75) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| Anthracene SCHEMBL7269976 | 0.82 | MAPK8 (0.63) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| SCHEMBL22720171 | 0.81 | TAS2R14 (0.74) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 | |
| SCHEMBL8416271 | 0.81 | RXFP1 (0.81) | RXFP1GRIK1MPO | |
| SCHEMBL6813056 | 0.80 | TAS2R14 (0.77) | TAS2R14ADRA2BADRA2CAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |