Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.73 |
| ▸ | MPO | P05164 | 6/20 | 0.71 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.71 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.70 |
| ▸ | YAP1 | P46937 | 1/20 | 0.70 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.70 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenamic Acid SCHEMBL29356958 | 0.99 | RXFP1 (0.75) | RXFP1MPOGRIK1TEAD4YAP1 | |
| Flufenamic Acid SCHEMBL17497 | 0.99 | RXFP1 (0.75) | RXFP1MPOGRIK1TEAD4YAP1 | |
| Flufenamic Acid SCHEMBL11524554 | 0.97 | RXFP1 (0.73) | RXFP1MPOGRIK1TEAD4YAP1 | |
| SCHEMBL8416271 | 0.91 | RXFP1 (0.81) | RXFP1MPOGRIK1 | |
| Flufenamic Acid SCHEMBL10531046 | 0.88 | MPO (0.67) | RXFP1MPOGRIK1TEAD4YAP1 | |
| SCHEMBL19002050 | 0.87 | TAS2R14 (0.62) | RXFP1MPOGRIK1TEAD4YAP1 | |
| SCHEMBL11330727 | 0.87 | TAS2R14 (0.82) | RXFP1MPOGRIK1TAS2R14AKR1C3 | |
| SCHEMBL19657901 | 0.86 | RXFP1 (0.70) | RXFP1MPOGRIK1TEAD4YAP1 | |
| SCHEMBL9522037 | 0.86 | YAP1 (0.74) | RXFP1MPOGRIK1TEAD4YAP1 | |
| SCHEMBL12851592 | 0.86 | RXFP1 (0.78) | RXFP1MPOTEAD4YAP1TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405602-A1 | New Zinc derivatives of anti-inflammatory drugs having improved therapeutic activity | LABORATORIOS VINAS S.A. (ES) | 1991-01-02 | — | — | EP | disclosed |