Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 13/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025815 | 0.94 | KCNH2 (0.34) | KCNH2TMEM97SIGMAR1NAMPTDPP8 | |
| SCHEMBL1024858 | 0.92 | AHCY (0.36) | NAMPTAHCY | |
| SCHEMBL1026233 | 0.90 | KDM5A (0.33) | KCNH2TMEM97SIGMAR1NAMPTDPP8 | |
| SCHEMBL1025869 | 0.88 | KCNH2 (0.34) | KCNH2TMEM97SIGMAR1NAMPTDPP8 | |
| SCHEMBL1082094 | 0.85 | AHCY (0.37) | NAMPTAHCY | |
| SCHEMBL1029885 | 0.84 | NAMPT (0.36) | NAMPTDPP8DPP9DPP4DPP7 | |
| SCHEMBL1028125 | 0.83 | AHCY (0.33) | KCNH2TMEM97SIGMAR1NAMPTDPP8 | |
| SCHEMBL1028282 | 0.83 | AHCY (0.31) | KCNH2TMEM97SIGMAR1NAMPTDPP8 | |
| SCHEMBL1026417 | 0.83 | KCNH2 (0.32) | KCNH2TMEM97SIGMAR1DPP8DPP9 | |
| SCHEMBL1027469 | 0.81 | AHCY (0.37) | NAMPTAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513235-B2 | Homocysteine synthase inhibitor | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20120196824-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196824-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | FABP7, TIMP3, MMP11 | KCNH2 3079/4885TMEM97 2107/4885SIGMAR1 3532/4885 |
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | BHMT, CBS, BHMT2 | KCNH2 3827/4885TMEM97 4359/4885SIGMAR1 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.