SCHEMBL1027276

SCHEMBL1027276

N#Cc1[nH][c]c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
KMT2A Q03164 1/20 0.34
IMPDH2 P12268 1/20 0.34
IMPDH1 P20839 1/20 0.34
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6467371 0.67 CHRNB2 (0.33)
SCHEMBL6465925 0.64 CHRNB2 (0.45) ALDH1A1KDM4EMEN1GAAKMT2A
SCHEMBL2969026 0.64 ESR1 (0.41) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL2071356 0.62 IMPDH2 (0.42) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL5748883 0.62 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL10774580 0.60 ALDH1A1 (0.42) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL20265243 0.60 KDM4E (0.46) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL13518915 0.60 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL1022617 0.60 IMPDH2 (0.44) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL29635217 0.58 PDE9A (0.49) ALDH1A1KDM4EMAPTMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183060-B2 comprises biotin covalently attached to a polymer that has monosaccharide or amino acid as a constituent monomer covalently attached to a luminescent substance (cyanoisoindoles, luminols, and acridinium esters); detecting a target substance at high sensitivity DAIICHI PURE CHEMICALS CO., LTD. (JP) 2012-05-22 US disclosed
EP-1437594-B1 LUMINESCENT POLYMER AND USE THEREOF IN BIOASSAY SEKISUI MEDICAL CO LTD (JP) 2011-01-12 EP disclosed
US-20050019573-A1 comprises biotin covalently attached to a polymer that has monosaccharide or amino acid as a constituent monomer covalently attached to a luminescent substance (cyanoisoindoles, luminols, and acridinium esters); detecting a target substance at high sensitivity DAIICHI PURE CHEMICALS CO., LTD. (JP) 2005-01-27 US disclosed
EP-1437594-A1 LUMINESCENT POLYMER AND USE THEREOF IN BIOASSAY DAIICHI PURE CHEMICALS CO., LTD. (JP) 2004-07-14 EP disclosed