Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905039 | 0.87 | KIF11 (0.47) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4088865 | 0.85 | EGFR (0.48) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL19707622 | 0.84 | RAB9A (0.76) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL7479983 | 0.83 | NR1H4 (0.59) | KIF11SMN1; SMN2MEN1KMT2ACRHBP | |
| SCHEMBL12894479 | 0.83 | KIF11 (0.58) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4638093 | 0.83 | RAB9A (0.58) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL2096251 | 0.83 | KIF11 (0.61) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL104524 | 0.83 | SMN1; SMN2 (0.61) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4105821 | 0.82 | RAB9A (0.67) | KIF11RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11124866 | 0.82 | HSD17B10 (0.51) | RAB9ASMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068295-B1 | A NEW HERBICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-08-28 | — | — | EP | claimed |
| EP-0068295-A1 | A new herbicidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | claimed |
| US-20150144521-A1 | STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE | RKW SE (DE) | 2015-05-28 | — | — | US | disclosed |
| US-20130096316-A1 | Novel Method for Preparation of Bisnorcymerine and Salts Thereof | QR PHARMA, INC. | 2013-04-18 | — | — | US | disclosed |
| US-20130017582-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-8338143-B2 | Enhanced production of paclitaxel and taxanes by cell cultures of Taxus species | PHYTON HOLDINGS, LLC (US) | 2012-12-25 | — | — | US | disclosed |
| WO-2012058031-A2 | NOVEL METHOD FOR PREPARATION OF BISNORCYMERINE AND SALTS THEREOF | QR PHARMA, INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| CN-101490004-B | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2012-01-11 | — | — | CN | disclosed |
| US-20110086397-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2011-04-14 | — | — | US | disclosed |
| EP-2044023-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDYNYL ALKYLENE ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA (IT) | 2011-01-19 | — | — | EP | disclosed |
| EP-0205271-B1 | N-(3-CHLORO-4-ISOPROPYLPHENYL)CARBOXAMIDES, PROCESS FOR PRODUCING THEM, AND SELECTIVE HERBICIDES CONTAINING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-02-01 | — | — | EP | disclosed |
| US-4749812-A | N-(3-chloro-4-isopropylphenyl) carboxamide derivative and selective herbicide | MITSUI TOATSU CHEMICALS, INC. (JP) | 1988-06-07 | — | — | US | disclosed |
| EP-0205271-A1 | N-(3-chloro-4-isopropylphenyl)carboxamides, process for producing them, and selective herbicides containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-12-17 | — | — | EP | disclosed |
| US-4390710-A | A 4-AMINOPYRIDINE WITH A PYRIDINE | PPG INDUSTRIES, INC. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0068295-A1 | A new herbicidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4308051-A | HERBICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4266070-A | CARBONYLS OF COBALT, MOLYBDENUM, TITANIUM, RHODIUM, IRON, NICKEL AND IRIDIUM AS CATALYSTS FOR THE CARBONYLATION OF PRIMARY OR SECONDARY AMINES AND ALCOHOLS TO FORM CARBAMATES | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-05-05 | — | — | US | disclosed |
| US-4029687-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-06-14 | — | — | US | disclosed |
| US-4004914-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096316-A1 | Novel Method for Preparation of Bisnorcymerine and Salts Thereof | PHOSPHO1, CBS, COASY | KIF11 4105/4885RAB9A 2162/4885SMN1; SMN2 4422/4885 |
| US-20150144521-A1 | STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE | ECPAS, BROX, TTPA | KIF11 3732/4885RAB9A 2428/4885SMN1; SMN2 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.