Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1390684 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTTSHRCYP3A4CYP2D6 | |
| SCHEMBL10280561 | 0.82 | ERN1 (0.48) | ALDH1A1MAPTTSHRCYP3A4CYP2D6 | |
| SCHEMBL10280160 | 0.81 | RARG (0.46) | ALDH1A1MAPTTSHRCYP3A4CYP2D6 | |
| SCHEMBL7922447 | 0.77 | TDP1 (0.51) | ALDH1A1MAPTKMT2AKDM4ETP53 | |
| SCHEMBL8131795 | 0.76 | RAB9A (0.48) | ALDH1A1MAPTTSHRCYP3A4CYP2D6 | |
| SCHEMBL7923604 | 0.76 | CHEK1 (0.47) | ALDH1A1MAPTCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7920254 | 0.75 | PLA2G2A (0.51) | ALDH1A1MAPTTSHRCYP3A4CYP2D6 | |
| SCHEMBL7920655 | 0.75 | MRGPRX4 (0.45) | MAPTKDM4ETDP1PTGER4 | |
| SCHEMBL7928723 | 0.75 | PLA2G2A (0.50) | ALDH1A1MAPTTSHRKDM4EHSD17B10 | |
| SCHEMBL11942537 | 0.74 | KDM4E (0.47) | ALDH1A1MAPTTSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010247-A1 | BICYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010247-A1 | BICYCLIC COMPOUND | ACACA, CPT1B, ACACB | ALDH1A1 762/4885MAPT 3578/4885TSHR 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.