Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165928 | 1.00 | HSD17B1 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9XDH | |
| Phenol SCHEMBL28023686 | 0.88 | XDH (0.57) | HSD17B1HSD17B2CYP3A4CYP2C9XDH | |
| SCHEMBL1330201 | 0.87 | — | — | |
| SCHEMBL51546 | 0.87 | — | — | |
| SCHEMBL29566889 | 0.87 | — | — | |
| SCHEMBL2154026 | 0.87 | CLK4 (0.65) | XDHSLC22A12CLK4PTPN5GABRA1 | |
| SCHEMBL31398107 | 0.86 | HSD17B1 (0.68) | HSD17B1HSD17B2CYP3A4CYP2C9AR | |
| SCHEMBL322948 | 0.86 | MMP3 (0.63) | HSD17B1HSD17B2CYP3A4CYP2C9XDH | |
| SCHEMBL1029367 | 0.86 | HSD17B1 (0.68) | HSD17B1HSD17B2CYP3A4CYP2C9AR | |
| SCHEMBL7397116 | 0.85 | ENPP2 (0.52) | CYP3A4XDHSLC22A12CLK4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115558110-B | Polymer and preparation method thereof, gel and dielectric material | 宁夏清研高分子新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-115558110-A | Polymer, preparation method thereof, gel and dielectric material | 宁夏清研高分子新材料有限公司 | 2023-01-03 | — | — | CN | disclosed |
| EP-2576507-B1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2017-04-05 | — | — | EP | disclosed |
| US-8835418-B2 | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI (FR) | 2014-09-16 | — | — | US | disclosed |
| US-20130165422-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2013-06-27 | — | — | US | disclosed |
| EP-2576507-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011151808-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |
| EP-1957493-B1 | 8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS MONOAMINE REUPTAKE INHIBITORS | ORGANON NV (NL) | 2011-01-19 | — | — | EP | disclosed |
| US-7605170-B2 | 8-azabicyclo[3.2.1]octane derivatives | N.V. ORGANON (NL) | 2009-10-20 | — | — | US | disclosed |
| US-20070185156-A1 | 8-Azabicyclo[3.2.1]octane derivatives | N.V. ORGANON (NL) | 2007-08-09 | — | — | US | disclosed |
| US-5262052-A | Separation of polycyclic aromatic hydrocarbons | BRIGHAM YOUNG UNIVERSITY (US) | 1993-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165422-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | F7, MGMT, CA13 | HSD17B1 4081/4885HSD17B2 4187/4885CYP3A4 3590/4885 |
| US-20070185156-A1 | 8-Azabicyclo[3.2.1]octane derivatives | SLC22A8, SLCO1B3, SLCO1B1 | HSD17B1 1363/4885HSD17B2 1275/4885CYP3A4 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.