Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 3/20 | 0.39 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | GIPR | P48546 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035443 | 0.84 | AKT1 (0.41) | CHEK2OPRK1SSTR5 | |
| SCHEMBL1034167 | 0.84 | STAT3 (0.41) | CHEK2CCR2STAT3SSTR5 | |
| SCHEMBL2681643 | 0.80 | ACHE (0.42) | ACHEP2RY1CCR2STAT3SSTR5 | |
| SCHEMBL1029775 | 0.79 | HIF1A (0.46) | ACHEP2RY1CCR2STAT3SSTR5 | |
| SCHEMBL1031736 | 0.78 | STAT3 (0.41) | STAT3OPRK1SSTR5 | |
| SCHEMBL1847418 | 0.75 | PRKAA2 (0.44) | OPRK1SSTR5MCHR1 | |
| SCHEMBL1844021 | 0.74 | WNK1 (0.43) | CHEK2CCR2WNK1OPRK1DRD2 | |
| SCHEMBL1846809 | 0.72 | PRKAA2 (0.42) | ACHEOPRK1 | |
| SCHEMBL1034169 | 0.68 | HIF1A (0.51) | STAT3SSTR5 | |
| SCHEMBL2681756 | 0.68 | F10 (0.44) | ACHESSTR5MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |