Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 11/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310896 | 0.88 | MT-CO2 (0.58) | MT-CO2PTGS1PTGS2MEN1LMNA | |
| SCHEMBL13299189 | 0.87 | SMN1; SMN2 (0.51) | MT-CO2PTGS2MEN1LMNACYP1A2 | |
| SCHEMBL13318494 | 0.82 | P2RX7 (0.51) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL5655209 | 0.81 | NPC1 (0.65) | CYP1A2HPGDP2RX7 | |
| SCHEMBL12608897 | 0.79 | MT-CO2 (0.61) | MT-CO2PTGS1PTGS2MEN1USP2 | |
| SCHEMBL13653002 | 0.78 | MT-CO2 (0.57) | MT-CO2PTGS1PTGS2MEN1USP2 | |
| SCHEMBL28905877 | 0.77 | MT-CO2 (0.74) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL29940782 | 0.77 | MT-CO2 (0.74) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL18235578 | 0.77 | SMN1; SMN2 (0.59) | MEN1LMNAMAPTHPGDKMT2A | |
| SCHEMBL10518206 | 0.76 | MT-CO2 (0.73) | MT-CO2PTGS1PTGS2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
| US-7632866-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY (IL) | 2009-12-15 | — | — | US | disclosed |
| US-7632866-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY (IL) | 2009-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | MT-CO2 2891/4885PTGS1 850/4885PTGS2 1097/4885 |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | MT-CO2 2891/4885PTGS1 850/4885PTGS2 1097/4885 |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | KCNN2, KCNN1, KCNN3 | MT-CO2 2706/4885PTGS1 1182/4885PTGS2 1207/4885 |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | KCNN2, KCNN1, KCNN3 | MT-CO2 2706/4885PTGS1 1182/4885PTGS2 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.